IL-1 beta 抗体
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北京 101111
Quick Overview for IL-1 beta 抗体 (ABIN641016)
抗原
See all IL-1 beta (IL1B) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-Chicken IL-1 beta
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特异性
- This product recognizes chicken Interleukin 1 beta (chIL-1beta), which shares homology with mammalian IL-1beta. IL-1 is a major regulator in both innate and adaptive immune responses, plays an important role in the regulation of acute inflammation and has also been implicated in many other processes, including both fever and fibrinogen induction. The previous names by which IL-1 has been known includes lymphocyte activating factor, endogenous pyrogen, catabolin, hemopoietin-1, melanoma growth inhibition factor, and osteoclast activating factor, reflecting its widespread cell expression. Studies using chicken models have indicated physiological similarities between chIL-1beta and mammalian IL-1beta in relation to its neural distribution and several factors have been shown to induce chIL-1beta secretion, including protein kinase C (PKC), Calmodulin-dependent protein kinase, lipopolysaccharide, phorbol esters, calcium and silica. It neutralizes chicken IL-1 beta (1-2).
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产品特性
- Cytokines/Chemokines/Growth Factors/Receptors
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免疫原
- Antisera to chicken Interleukin 1 Beta were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography on protein G
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亚型
- IgG
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应用备注
- ELISA, Functional Assays, Western Blotting
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限制
- 仅限研究用
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浓度
- IgG concentration 0.5 mg/ml
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缓冲液
- Phosphate buffered saline
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- -20°C
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- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
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别名
- Interleukin-1 beta (IL-1b)
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途径
- NF-kappaB Signaling, Interferon-gamma Pathway, TLR signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
抗原
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