CHEK1 抗体
Quick Overview for CHEK1 抗体 (ABIN634171)
抗原
See all CHEK1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
纯化方法
- Affinity purified
-
免疫原
- CHEK1 antibody was raised using a synthetic peptide corresponding to a region with amino acids WSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLAL
-
-
-
-
应用备注
-
WB: 0.5 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator. -
说明
-
CHEK1 Blocking Peptide, (ABIN935960), is also available for use as a blocking control in assays to test for specificity of this CHEK1 antibody
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CHEK1 antibody in PBS
-
浓度
- Lot specific
-
缓冲液
- PBS
-
注意事项
- Avoid repeated freeze/thaw cycles.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
-
-
- CHEK1 (Checkpoint Kinase 1 (CHEK1))
-
别名
- CHEK1
-
背景
- CHEK1 is required during normal S phase to avoid aberrantly increased initiation of DNA replication, thereby protecting against DNA breakage. Its expression is dispensable for somatic cell death and critical for sustaining G2 DNA damage checkpoint.
-
分子量
- 54 kDa (MW of target protein)
-
途径
- p53 Pathway, Apoptosis, Cell Division Cycle, DNA Damage Repair
抗原
-