ADAMTS4 抗体 (N-Term)
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- 抗原 See all ADAMTS4 抗体
- ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ADAMTS4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- ADAMTS4 antibody was raised against the N terminal of ADAMTS4
- 纯化方法
- Affinity purified
- 免疫原
- ADAMTS4 antibody was raised using the N terminal of ADAMTS4 corresponding to a region with amino acids GVQVEGLTVQYLGQAPELLGGAEPGTYLTGTINGDPESVASLHWDGGALL
- Top Product
- Discover our top product ADAMTS4 Primary Antibody
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- 应用备注
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WB: 0.5 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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ADAMTS4 Blocking Peptide, catalog no. 33R-3654, is also available for use as a blocking control in assays to test for specificity of this ADAMTS4 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of ADAMTS4 antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))
- 别名
- ADAMTS4 (ADAMTS4 产品)
- 别名
- 3830423K05 antibody, ADAM-TS4 antibody, ADAMTS-2 antibody, ADMP-1 antibody, mKIAA0688 antibody, ADAMTS-4 antibody, ADAMTS4 antibody, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 antibody, ADAM metallopeptidase with thrombospondin type 1 motif 4 antibody, ADAM metallopeptidase with thrombospondin type 1 motif, 4 antibody, Adamts4 antibody, ADAMTS4 antibody
- 背景
- ADAMTS4 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. ADAMTS4 lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.
- 分子量
- 37 kDa (MW of target protein)
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