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ADAMTS4 抗体 (N-Term)

ADAMTS4 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN630877
发货至: 中国
  • 抗原 See all ADAMTS4 抗体
    ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))
    抗原表位
    • 15
    • 12
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    • 2
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    • 1
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    N-Term
    适用
    • 81
    • 48
    • 20
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    • 9
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    • 4
    • 4
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    人, 小鼠, 大鼠
    宿主
    • 73
    • 10
    • 4
    克隆类型
    • 78
    • 9
    多克隆
    标记
    • 41
    • 10
    • 8
    • 3
    • 2
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    • 2
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    • 2
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    • 2
    • 2
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    This ADAMTS4 antibody is un-conjugated
    应用范围
    • 64
    • 29
    • 15
    • 13
    • 13
    • 13
    • 11
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
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    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    ADAMTS4 antibody was raised against the N terminal of ADAMTS4
    纯化方法
    Affinity purified
    免疫原
    ADAMTS4 antibody was raised using the N terminal of ADAMTS4 corresponding to a region with amino acids GVQVEGLTVQYLGQAPELLGGAEPGTYLTGTINGDPESVASLHWDGGALL
    Top Product
    Discover our top product ADAMTS4 Primary Antibody
  • 应用备注
    WB: 0.5 µg/mL, IHC: 4-8 µg/mL
    Optimal conditions should be determined by the investigator.
    说明

    ADAMTS4 Blocking Peptide, catalog no. 33R-3654, is also available for use as a blocking control in assays to test for specificity of this ADAMTS4 antibody

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of ADAMTS4 antibody in PBS
    浓度
    Lot specific
    缓冲液
    PBS
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原
    ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))
    别名
    ADAMTS4 (ADAMTS4 产品)
    别名
    3830423K05 antibody, ADAM-TS4 antibody, ADAMTS-2 antibody, ADMP-1 antibody, mKIAA0688 antibody, ADAMTS-4 antibody, ADAMTS4 antibody, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 antibody, ADAM metallopeptidase with thrombospondin type 1 motif 4 antibody, ADAM metallopeptidase with thrombospondin type 1 motif, 4 antibody, Adamts4 antibody, ADAMTS4 antibody
    背景
    ADAMTS4 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. ADAMTS4 lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.
    分子量
    37 kDa (MW of target protein)
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