ADAMTS4 抗体 (N-Term)
(3 references)-
- 抗原 See all ADAMTS4 抗体
- ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 马, 犬, Cow, 豚鼠, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ADAMTS4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- GVQVEGLTVQ YLGQAPELLG GAEPGTYLTG TINGDPESVA SLHWDGGALL
- 预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against ADAMTS4. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ADAMTS4
- Top Product
- Discover our top product ADAMTS4 Primary Antibody
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anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) antibody
ADAMTS4 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) (AA 213-319) antibodyADAMTS4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) (Internal Region) antibodyADAMTS4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) (AA 705-736), (C-Term) antibodyADAMTS4 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB18037 unconjugated
anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) (AA 501-839) antibodyADAMTS4 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) (AA 437-575) antibodyADAMTS4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) (Metalloprotease Domain) antibodyADAMTS4 适用: 人, 马, 犬, 猴, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) (C-Term) antibodyADAMTS4 适用: 人, 马, 犬 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) (Disintegrin-like Domain) antibodyADAMTS4 适用: 人, 小鼠, 马, 犬, 猴, Cow, 豚鼠, Bat, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) (Internal Region) antibodyADAMTS4 适用: 人, 小鼠, 大鼠, 马, 犬, 猴, Cow, Bat, Pig IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 339 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Differential expression patterns of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) -1, -4, -5, and -14 in human placenta and gestational trophoblastic diseases." in: Archives of pathology & laboratory medicine, Vol. 138, Issue 5, pp. 643-50, (2014) (PubMed).
: "Comparison of ADAMTS-1, -4 and -5 expression in culprit plaques between acute myocardial infarction and stable angina." in: Journal of clinical pathology, Vol. 64, Issue 5, pp. 399-404, (2011) (PubMed).
: "Partially redundant functions of Adamts1 and Adamts4 in the perinatal development of the renal medulla." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 240, Issue 7, pp. 1806-14, (2011) (PubMed).
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: "Differential expression patterns of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) -1, -4, -5, and -14 in human placenta and gestational trophoblastic diseases." in: Archives of pathology & laboratory medicine, Vol. 138, Issue 5, pp. 643-50, (2014) (PubMed).
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- 抗原
- ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))
- 别名
- ADAMTS4 (ADAMTS4 产品)
- 别名
- 3830423K05 antibody, ADAM-TS4 antibody, ADAMTS-2 antibody, ADMP-1 antibody, mKIAA0688 antibody, ADAMTS-4 antibody, ADAMTS4 antibody, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 antibody, ADAM metallopeptidase with thrombospondin type 1 motif 4 antibody, ADAM metallopeptidase with thrombospondin type 1 motif, 4 antibody, Adamts4 antibody, ADAMTS4 antibody
- 背景
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ADAMTS4 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. ADAMTS4 lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.
Alias Symbols: ADAMTS-2, ADAMTS-4, ADMP-1, KIAA0688
Protein Interaction Partner: YTHDC1, ZBTB16, ELAVL1, UBC, MT2A, SRPX2, ADAMTS4, BCAN, SERPINA1, ACAN, HP, FURIN, FN1, SERPINA3,
Protein Size: 339 - 分子量
- 37 kDa
- 基因ID
- 9507
- UniProt
- Q8NEK2
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