ADAMTS4 抗体 (AA 501-839)
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- 抗原 See all ADAMTS4 抗体
- ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))
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抗原表位
- AA 501-839
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ADAMTS4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- Due to the similarity this protein to ADAMTS1, there is a chance that this antibody may have a cross-reactivity with this protein, based upon a 73 % sequence similarity in the epitope region.
- 交叉反应
- 人, 小鼠
- 预测反应
- Rat,Cow,Sheep,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ADAMTS4
- 亚型
- IgG
- Top Product
- Discover our top product ADAMTS4 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))
- 别名
- ADAMTS4 (ADAMTS4 产品)
- 别名
- 3830423K05 antibody, ADAM-TS4 antibody, ADAMTS-2 antibody, ADMP-1 antibody, mKIAA0688 antibody, ADAMTS-4 antibody, ADAMTS4 antibody, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 antibody, ADAM metallopeptidase with thrombospondin type 1 motif 4 antibody, ADAM metallopeptidase with thrombospondin type 1 motif, 4 antibody, Adamts4 antibody, ADAMTS4 antibody
- 背景
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Synonyms: ADMP-1, ADAMTS-2, ADAMTS-4, A disintegrin and metalloproteinase with thrombospondin motifs 4, ADAM-TS 4, ADAM-TS4, Aggrecanase-1, ADAMTS4, KIAA0688, UNQ769/PRO1563
Background: Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-|-Ala-393' site.
- 基因ID
- 9507
- UniProt
- O75173
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