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Insulin 抗体

INS 适用: 人, Pig, 小鼠, Cow, 兔 IHC, IF, FACS 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN6297594
发货至: 中国
  • 抗原 See all Insulin (INS) 抗体
    Insulin (INS)
    适用
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    • 106
    • 91
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    人, Pig, 小鼠, Cow, 兔
    宿主
    • 137
    • 86
    • 13
    • 2
    • 1
    • 1
    小鼠
    克隆类型
    • 144
    • 98
    单克隆
    标记
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    This Insulin antibody is un-conjugated
    应用范围
    • 83
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    Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
    原理
    Mouse anti-Human/Cow/Pig/Rabbit/Mouse Insulin Antibody [Sodium Azide Free]
    特异性
    Cytoplasmic
    纯化方法
    Recombinant INS protein was used as the immunogen for the Insulin antibody.
    免疫原
    Recombinant INS protein was used as the immunogen for the Insulin antibody.
    Top Product
    Discover our top product INS Primary Antibody
  • 应用备注
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 1-2 μg/mL
    Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
    Prediluted format: incubate for 30 min at RT (2)
    限制
    仅限研究用
  • 缓冲液
    In 1X PBS, BSA free, sodium azide free
    储存液
    Azide free
    储存条件
    4 °C,-20 °C
    储存方法
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原
    Insulin (INS)
    别名
    Insulin (INS 产品)
    别名
    IDDM2 antibody, ILPR antibody, IRDN antibody, MODY10 antibody, ins1 antibody, xins antibody, ins1-a antibody, Insulin antibody, AA986540 antibody, Ins-2 antibody, InsII antibody, Mody antibody, Mody4 antibody, proinsulin antibody, zgc:109842 antibody, igf2-A antibody, ins antibody, ins-a antibody, ins-b antibody, insulin antibody, insulin precursor antibody, insulin II antibody, preproinsulin antibody, insulin L homeolog antibody, insulin S homeolog antibody, INS antibody, INS-IGF2 antibody, ins antibody, Ins antibody, PIN antibody, Ins2 antibody, ins.L antibody, ins.S antibody
    背景

    Target Description: Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.

    Gene Symbol: INS

    基因ID
    3630
    UniProt
    P01308
    途径
    NF-kappaB Signaling, RTK signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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