MBTPS1 抗体
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- 抗原 See all MBTPS1 抗体
- MBTPS1 (Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MBTPS1 antibody is un-conjugated
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应用范围
- Immunofluorescence (IF)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human MBTPS1
- 亚型
- IgG
- Top Product
- Discover our top product MBTPS1 Primary Antibody
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- 应用备注
- IF 1:50 - 1:200
- 说明
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Widely expressed
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20C. Avoid freeze / thaw cycles.
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- 抗原
- MBTPS1 (Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1))
- 别名
- MBTPS1 (MBTPS1 产品)
- 别名
- PCSK8 antibody, S1P antibody, SKI-1 antibody, 0610038M03Rik antibody, AV003995 antibody, Ski1 antibody, mKIAA0091 antibody, S1p antibody, Ski-1 antibody, membrane bound transcription factor peptidase, site 1 antibody, membrane-bound transcription factor peptidase, site 1 antibody, MBTPS1 antibody, Mbtps1 antibody
- 背景
- This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction.
- 分子量
- 117.749 kDa
- 基因ID
- 8720
- UniProt
- Q14703
- 途径
- ER-Nucleus Signaling
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