MBTPS1 产品
(Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1))
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The encoded protein has a central role in the regulation of lipid metabolism in cells. It is a sterol-regulated subtilisin-like serine protease that cleaves ER membrane-bound sterol regulatory element-binding proteins (SREBPs), a reaction that initiates the two-step proteolytic process by which transcriptionally active fragments of SREBPs are released from the membrane for translocation to the nucleus. The gene product is an integral membrane ER protein, with the bulk located in the ER lumen. It is synthesized as an inactive preproprotein that is self-activated by an intramolecular cleavage that generates the mature protein. [provided by RefSeq, Jul 2008].
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Featured MBTPS1 Categories
Recommended MBTPS1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, IF
Validations
- (4)
Cat. No.
ABIN7256896
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, WB, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6259458
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7166091
Quantity
100 μg
Datasheet
Datasheet
Recommended MBTPS1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310499
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310498
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3093760
Quantity
1 mg
Datasheet
Datasheet
Synonyms and alternative names related to MBTPS1
membrane bound transcription factor peptidase, site 1 (MBTPS1), membrane-bound transcription factor peptidase, site 1 (Mbtps1), 0610038M03Rik, AV003995, mKIAA0091, PCSK8, S1P, S1p, SKI-1, Ski-1, Ski1Protein level used designations for MBTPS1
- endopeptidase S1P
- membrane-bound transcription factor site-1 protease
- site-1 protease
- subtilisin/kexin isozyme-1
- S1P endopeptidase
- membrane-bound transcription factor protease, site 1
- sterol-regulated luminal protease
- subtilisin/kexin isozyme 1
- subtilisin/kexin isozyme SKI-1
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