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- 抗原 See all ABCB1 抗体
- ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ABCB1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic peptide of human ABCB1
- 亚型
- IgG
- Top Product
- Discover our top product ABCB1 Primary Antibody
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anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 995-1280) antibody
ABCB1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2C7 unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 995-1280) antibodyABCB1 适用: 人 IHC, IHC (p) 宿主: 小鼠 Monoclonal 5B3 unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) antibodyABCB1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 236-297) antibodyABCB1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 1149-1280) antibodyABCB1 适用: 人 WB, IHC, ELISA, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 4G6F4 unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 632-693) antibodyABCB1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6G11C12 unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 863-912) antibodyABCB1 适用: 人, 小鼠, 大鼠, 兔, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 630-710) antibodyABCB1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (Internal Region) antibodyABCB1 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (Middle Region) antibodyABCB1 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, Pig, 绵羊, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:500 - 1:2000
IHC 1:50 - 1:200 - 说明
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Expressed in liver, kidney, small intestine and brain
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20C. Avoid freeze / thaw cycles.
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- 抗原
- ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))
- 别名
- ABCB1 (ABCB1 产品)
- 别名
- ABC20 antibody, CD243 antibody, CLCS antibody, GP170 antibody, MDR1 antibody, P-GP antibody, PGY1 antibody, Abcb1 antibody, Mdr1a antibody, p-gp antibody, xemdr antibody, Mdr1 antibody, Mdr1b antibody, Pgy-1 antibody, Pgy1 antibody, mdr antibody, ABCB1 antibody, PGP1 antibody, ATP binding cassette subfamily B member 1 antibody, ATP binding cassette subfamily B member 1A antibody, ATP binding cassette subfamily B member 1 L homeolog antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 1B antibody, ABCB1 antibody, Abcb1a antibody, abcb1.L antibody, Abcb1b antibody, Abcb1 antibody
- 背景
- The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. Mutations in this gene are associated with colchicine resistance and Inflammatory bowel disease 13. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
- 分子量
- 141.479 kDa
- 基因ID
- 5243
- UniProt
- P08183
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