ABCB1 抗体 (AA 632-693)
-
- 抗原 See all ABCB1 抗体
- ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))
-
抗原表位
- AA 632-693
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This ABCB1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human ABCB1 (AA: 632-693) expressed in E. coli.
- 克隆位点
- 6G11C12
- 亚型
- IgG1
- Top Product
- Discover our top product ABCB1 Primary Antibody
-
-
- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
-
-
Study of ABCB1 polymorphism frequency in breast cancer patients from Poland." in: Pharmacological reports : PR, Vol. 64, Issue 6, pp. 1560-6, (2013) (PubMed).
: "Downregulation of gene MDR1 by shRNA to reverse multidrug-resistance of ovarian cancer A2780 cells." in: Journal of cancer research and therapeutics, Vol. 8, Issue 2, pp. 226-31, (2012) (PubMed).
: "
-
Study of ABCB1 polymorphism frequency in breast cancer patients from Poland." in: Pharmacological reports : PR, Vol. 64, Issue 6, pp. 1560-6, (2013) (PubMed).
-
- 抗原
- ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))
- 别名
- ABCB1 (ABCB1 产品)
- 别名
- ABC20 antibody, CD243 antibody, CLCS antibody, GP170 antibody, MDR1 antibody, P-GP antibody, PGY1 antibody, Abcb1 antibody, Mdr1a antibody, p-gp antibody, xemdr antibody, Mdr1 antibody, Mdr1b antibody, Pgy-1 antibody, Pgy1 antibody, mdr antibody, ABCB1 antibody, PGP1 antibody, ATP binding cassette subfamily B member 1 antibody, ATP binding cassette subfamily B member 1A antibody, ATP binding cassette subfamily B member 1 L homeolog antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 1B antibody, ABCB1 antibody, Abcb1a antibody, abcb1.L antibody, Abcb1b antibody, Abcb1 antibody
- 背景
-
Description: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. ,
Aliases: CLCS, MDR1, P-GP, PGY1, ABC20, CD243, GP170
- 分子量
- 141.5 kDa
- 基因ID
- 5243
- HGNC
- 5243
-