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ABCB1 抗体

ABCB1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7265732
发货至: 中国
  • 抗原 See all ABCB1 抗体
    ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))
    适用
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    宿主
    • 46
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    克隆类型
    • 44
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    单克隆
    标记
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    This ABCB1 antibody is un-conjugated
    应用范围
    • 37
    • 23
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    • 19
    • 15
    • 13
    • 10
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    • 3
    • 2
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    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    P Glycoprotein Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human P Glycoprotein
    亚型
    IgG
    Top Product
    Discover our top product ABCB1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))
    别名
    ABCB1 (ABCB1 产品)
    别名
    ABC20 antibody, CD243 antibody, CLCS antibody, GP170 antibody, MDR1 antibody, P-GP antibody, PGY1 antibody, Abcb1 antibody, Mdr1a antibody, p-gp antibody, xemdr antibody, Mdr1 antibody, Mdr1b antibody, Pgy-1 antibody, Pgy1 antibody, mdr antibody, ABCB1 antibody, PGP1 antibody, ATP binding cassette subfamily B member 1 antibody, ATP binding cassette subfamily B member 1A antibody, ATP binding cassette subfamily B member 1 L homeolog antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 1B antibody, ABCB1 antibody, Abcb1a antibody, abcb1.L antibody, Abcb1b antibody, Abcb1 antibody
    背景
    The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. Mutations in this gene are associated with colchicine resistance and Inflammatory bowel disease 13. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Feb 2017],ABC20,CD243,CLCS,GP170,MDR1,P-GP,PGY1,P Glycoprotein,ABCB1,Cancer,CDs,Drug resistance,Drug resistance_P glycoproteins,Endocrine & Metabolism,Hematopoietic Progenitors,Immunology & Inflammation,Signal Transduction,Stem Cells,ABCB1
    分子量
    134kDa/141kDa
    基因ID
    5243
    UniProt
    P08183
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