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SIRT1 抗体

SIRT1 适用: 人, 小鼠, 大鼠 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6291361
发货至: 中国
  • 抗原 See all SIRT1 抗体
    SIRT1 (Sirtuin 1 (SIRT1))
    适用
    • 139
    • 88
    • 57
    • 34
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 125
    • 20
    • 2
    • 2
    • 1
    克隆类型
    • 112
    • 38
    多克隆
    标记
    • 71
    • 14
    • 10
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    This SIRT1 antibody is un-conjugated
    应用范围
    • 122
    • 50
    • 50
    • 41
    • 39
    • 35
    • 24
    • 22
    • 18
    • 13
    • 9
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human SIRT1
    亚型
    IgG
    Top Product
    Discover our top product SIRT1 Primary Antibody
  • 应用备注
    WB 1:500 - 1:2000
    IHC 1:50 - 1:200
    IP 1:50 - 1:100
    说明

    Widely expressed

    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20C. Avoid freeze / thaw cycles.
  • 抗原
    SIRT1 (Sirtuin 1 (SIRT1))
    别名
    SIRT1 (SIRT1 产品)
    别名
    sirtuin 1 antibody, AA673258 antibody, SIR2L1 antibody, Sir2 antibody, Sir2a antibody, Sir2alpha antibody, sir2l1 antibody, sirtuin antibody, SIR2 antibody, sirtuin 1 antibody, sirtuin 1 L homeolog antibody, SIRT1 antibody, SRT1 antibody, Sirt1 antibody, sirt1.L antibody
    背景
    This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.
    分子量
    81.681 kDa
    基因ID
    23411
    UniProt
    Q96EB6
    途径
    MAPK Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling
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