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VEGFA 抗体 (Internal Region)

VEGFA 适用: 人, 大鼠, 小鼠 ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6287156
发货至: 中国
  • 抗原 See all VEGFA 抗体
    VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
    抗原表位
    • 19
    • 15
    • 15
    • 15
    • 15
    • 15
    • 10
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    Internal Region
    适用
    • 155
    • 126
    • 98
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    人, 大鼠, 小鼠
    宿主
    • 204
    • 53
    • 13
    • 1
    克隆类型
    • 215
    • 55
    • 1
    多克隆
    标记
    • 122
    • 41
    • 25
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    This VEGFA antibody is un-conjugated
    应用范围
    • 206
    • 93
    • 65
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    • 32
    • 27
    • 22
    • 22
    • 16
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    ELISA, Immunofluorescence (IF)
    原理
    VEGFA is a protein encoded by the VEGFA gene which is approximately 27,1 kDa. VEGFA is freely secreted. It is involved in the response to elevated platelet cytosolic Ca2+, development VEGF signalling, CDK-mediated phosphorylation and removal of Cdc6 and RET signalling. It is a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Isoform VEGF189, VEGF165 and VEGF121 are widely expressed in human tissues. Mutations in the VEGFA gene may result in microvascular complications of diabetes. This gene is also upregulated in many known tumors. STJ96235 was affinity purified. This polyclonal antibody binds to VEGFA.
    特异性
    VEGF-A Polyclonal Antibody detects endogenous levels of VEGF-A protein.
    产品特性
    Rabbit polyclonal to VEGFA.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Synthesized peptide derived from human VEGF-A.
    亚型
    IgG
    Top Product
    Discover our top product VEGFA Primary Antibody
  • 应用备注
    IHC 1:100-1:300
    ELISA 1:10000
    说明

    Isoform VEGF189, isoform VEGF165 and isoform VEGF121 are widely expressed. Isoform VEGF206 and isoform VEGF145 are not widely expressed. A higher level expression seen in pituitary tumors as compared to the pituitary gland.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • 抗原
    VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
    别名
    VEGFA (VEGFA 产品)
    别名
    MVCD1 antibody, VEGF antibody, VPF antibody, Vegf antibody, Vegf120 antibody, Vegf164 antibody, Vegf188 antibody, Vpf antibody, vegf antibody, vegfa antibody, wu:fj82c06 antibody, VEGF-A antibody, VEGF164 antibody, eVEGF120 antibody, eVEGF164 antibody, vegf-a antibody, vpf antibody, vefg antibody, si:dkey-14d8.3 antibody, wu:fd42e02 antibody, vascular endothelial growth factor A antibody, vascular endothelial growth factor Aa antibody, vascular endothelial growth factor A L homeolog antibody, vascular endothelial growth factor Ab antibody, VEGFA antibody, Vegfa antibody, vegfaa antibody, vegfa.L antibody, vegfa antibody, vegfab antibody
    分子量
    27 kDa
    基因ID
    7422
    UniProt
    P15692
    途径
    RTK signaling, Glycosaminoglycan Metabolic Process, Regulation of Cell Size, Tube Formation, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
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