VEGFR2/CD309 抗体 (AA 890-970)
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- 抗原 See all VEGFR2/CD309 (VEGFR2) 抗体
- VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
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抗原表位
- AA 890-970
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This VEGFR2/CD309 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Flk-1 is a protein encoded by the KDR gene which is approximately 151,5 kDa. Flk-1 isoform 1 is localised to the cell membrane and isoform 2 and 3 are secreted. It is involved in apoptotic pathways, the GPCR pathway, ERK signalling and the CREB pathway. This receptor is one of two type III receptor tyrosine kinase that functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor. Flk-1 is widely expressed in human tissues including the cornea. Mutations in the KDR gene may result in hemangioma. STJ93088 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Flk-1 protein.
- 特异性
- Flk-1 Polyclonal Antibody detects endogenous levels of Flk-1 protein.
- 产品特性
- Rabbit polyclonal to Flk-1.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from human Flk-1 around the non-phosphorylation site of Y951.
- 亚型
- IgG
- Top Product
- Discover our top product VEGFR2 Primary Antibody
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- 应用备注
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WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000 - 说明
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Detected in cornea (at protein level). Widely expressed.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- 抗原
- VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
- 别名
- Flk-1 (VEGFR2 产品)
- 别名
- CD309 antibody, FLK1 antibody, VEGFR antibody, VEGFR2 antibody, 6130401C07 antibody, Flk-1 antibody, Flk1 antibody, Krd-1 antibody, Ly73 antibody, VEGFR-2 antibody, sVEGFR-2 antibody, Vegfr-2 antibody, FLK-1 antibody, flk-1 antibody, vegfr-2 antibody, KDR antibody, FLK/KDR antibody, flk1 antibody, flk1b antibody, kdrb antibody, si:busm1-205d10.1 antibody, si:ch211-254j6.1 antibody, si:ch211-278f21.4 antibody, wu:fc31a09 antibody, fk52c05 antibody, flk antibody, kdr antibody, kdra antibody, vegfr2 antibody, vegfr4 antibody, vegr2 antibody, wu:fk52c05 antibody, kinase insert domain receptor antibody, kinase insert domain protein receptor antibody, vascular endothelial growth factor receptor kdr-like antibody, kinase insert domain receptor (a type III receptor tyrosine kinase) antibody, kinase insert domain receptor like antibody, KDR antibody, Kdr antibody, LOC100136647 antibody, kdr antibody, kdrl antibody
- 分子量
- 151 kDa
- 基因ID
- 3791
- UniProt
- P35968
- 途径
- RTK signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
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