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FASL 抗体 (Internal Region)

FASL 适用: 人, 小鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6284867
发货至: 中国
  • 抗原 See all FASL 抗体
    FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
    抗原表位
    • 16
    • 9
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 70-150, Internal Region
    适用
    • 94
    • 42
    • 31
    • 18
    • 6
    • 4
    • 3
    • 2
    • 1
    人, 小鼠
    宿主
    • 66
    • 27
    • 8
    • 4
    • 4
    • 1
    克隆类型
    • 73
    • 37
    多克隆
    标记
    • 62
    • 12
    • 9
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FASL antibody is un-conjugated
    应用范围
    • 74
    • 49
    • 25
    • 22
    • 20
    • 16
    • 13
    • 13
    • 9
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    FAS-L is a protein encoded by the FASLG gene which is approximately 31,4 kDa. FAS-L is localised to the cell membrane and is involved in PEDF induced signalling, dimerization of procaspase-8, apoptosis modulation and signalling and the TNFR1 pathway. FAS-L is a member of the tumor necrosis factor superfamily. It is a cytokine that binds to TNFRSF6/FAS which is a receptor that transduces the apoptotic signal into cells. It may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. FAS-L is expressed in the blood, spleen, lymph nodes, intestine and kidney. Mutations in the FASLG gene result in autoimmune lymphoproliferative syndrome 1B. STJ93042 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of FAS-L protein.
    特异性
    FAS-L Polyclonal Antibody detects endogenous levels of FAS-L protein.
    产品特性
    Rabbit polyclonal to FAS-L.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Synthesized peptide derived from human FAS-L
    亚型
    IgG
    Top Product
    Discover our top product FASL Primary Antibody
  • 应用备注
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • 抗原
    FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
    别名
    FAS-L (FASL 产品)
    别名
    ALPS1B antibody, APT1LG1 antibody, APTL antibody, CD178 antibody, CD95-L antibody, CD95L antibody, FASL antibody, TNFSF6 antibody, fasl antibody, Fas-L antibody, Faslg antibody, Tnfsf6 antibody, gld antibody, Apt1Lg1 antibody, Fasl antibody, FASLG antibody, zgc:162027 antibody, Fas ligand antibody, Fas ligand L homeolog antibody, Fas ligand (TNF superfamily, member 6) antibody, FASLG antibody, faslg.L antibody, Fasl antibody, Faslg antibody, faslg antibody
    分子量
    33 kDa
    基因ID
    356
    UniProt
    P48023
    途径
    Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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