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AIRE 抗体 (Ser156)

AIRE 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6280595
发货至: 中国
  • 抗原 See all AIRE 抗体
    AIRE (Autoimmune Regulator (AIRE))
    抗原表位
    • 10
    • 9
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 100-180, Ser156
    适用
    • 51
    • 23
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    宿主
    • 46
    • 7
    • 1
    克隆类型
    • 53
    多克隆
    标记
    • 38
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AIRE antibody is un-conjugated
    应用范围
    • 39
    • 24
    • 19
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    原理
    Rabbit polyclonal to AIRE-1.
    特异性
    AIRE-1 Polyclonal Antibody detects endogenous levels of AIRE-1 protein.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Synthesized peptide derived from human AIRE-1 around the non-phosphorylation site of S156.
    亚型
    IgG
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    Discover our top product AIRE Primary Antibody
  • 应用备注
    WB 1:500-1:2000
    ELISA 1:5000
    说明

    Widely expressed. Expressed at higher level in thymus (medullary epithelial cells and monocyte-dendritic cells), pancreas, adrenal cortex and testis. Expressed at lower level in the spleen, fetal liver and lymph nodes. In secondary lymphoid organs, expressed in a discrete population of bone marrow-derived toleregenic antigen presenting cells (APCs) called extrathymic AIRE expressing cells (eTAC)(at protein level) . Isoform 2 and isoform 3 seem to be less frequently expressed than isoform 1, if at all.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • 抗原
    AIRE (Autoimmune Regulator (AIRE))
    别名
    AIRE-1 (AIRE 产品)
    别名
    AIRE1 antibody, APECED antibody, APS1 antibody, APSI antibody, PGA1 antibody, autoimmune regulator antibody, autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) antibody, AaeL_AAEL013794 antibody, CpipJ_CPIJ001208 antibody, CpipJ_CPIJ001209 antibody, AIRE antibody, Aire antibody
    分子量
    50 kDa
    基因ID
    326
    UniProt
    O43918
    途径
    Chromatin Binding
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