AIRE 抗体 (Ser156)
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- 抗原 See all AIRE 抗体
- AIRE (Autoimmune Regulator (AIRE))
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抗原表位
- AA 100-180, Ser156
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AIRE antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 原理
- Rabbit polyclonal to AIRE-1.
- 特异性
- AIRE-1 Polyclonal Antibody detects endogenous levels of AIRE-1 protein.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from human AIRE-1 around the non-phosphorylation site of S156.
- 亚型
- IgG
- Top Product
- Discover our top product AIRE Primary Antibody
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- 应用备注
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WB 1:500-1:2000
ELISA 1:5000 - 说明
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Widely expressed. Expressed at higher level in thymus (medullary epithelial cells and monocyte-dendritic cells), pancreas, adrenal cortex and testis. Expressed at lower level in the spleen, fetal liver and lymph nodes. In secondary lymphoid organs, expressed in a discrete population of bone marrow-derived toleregenic antigen presenting cells (APCs) called extrathymic AIRE expressing cells (eTAC)(at protein level) . Isoform 2 and isoform 3 seem to be less frequently expressed than isoform 1, if at all.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- 抗原
- AIRE (Autoimmune Regulator (AIRE))
- 别名
- AIRE-1 (AIRE 产品)
- 别名
- AIRE1 antibody, APECED antibody, APS1 antibody, APSI antibody, PGA1 antibody, autoimmune regulator antibody, autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) antibody, AaeL_AAEL013794 antibody, CpipJ_CPIJ001208 antibody, CpipJ_CPIJ001209 antibody, AIRE antibody, Aire antibody
- 分子量
- 50 kDa
- 基因ID
- 326
- UniProt
- O43918
- 途径
- Chromatin Binding
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