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Src 抗体 (pSer75)

Name: Src 抗体 (pSer75)
Brand: antibodies-online
SKU: ABIN6280569
Availability: OutOfStock

Src 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

产品编号 ABIN6280569

发货至: 中国

Datasheet as PDF

抗原 See all Src 抗体

Src (Proto-oncogene tyrosine-protein kinase Src (Src))
抗原表位
27

25

20

20

19

18

15

14

11

8

7

6

4

4

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 10-90, pSer75
适用
215

142

119

9

7

7

5

5

5

4

3

2

1

1

1
人, 小鼠, 大鼠
宿主
228

19

1
兔
Compatible Secondaries
克隆类型
216

32
多克隆
标记
117

21

17

16

11

10

6

6

6

6

6

6

4

4

4

4

4
This Src antibody is un-conjugated
应用范围
188

133

62

55

53

33

29

24

22

12

9

6

4

3

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

原理

c-Src is a protein encoded by the SRC gene which is approximately 59,8 kDa. c-Src is localised to the cell membrane and mitochondria inner membrane. It is involved RET signalling, negative regulation of FGFR1 signalling, EPH-Ephrin signalling and GAB1 signalosome. It is a non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein-coupled receptors as well as cytokine receptors. c-Src is expressed ubiquitously. Mutations in the SRC gene result in thrombocytopenia. STJ90958 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody specifically binds to endogenous c-Src protein which only binds about S75 when S75 is phosphorylated.

特异性

Phospho-c-Src (S75) Polyclonal Antibody detects endogenous levels of c-Src protein only when phosphorylated at S75.

产品特性

Rabbit polyclonal to Phospho-c-Src (S75).

纯化方法

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

免疫原

Synthesized peptide derived from human c-Src around the phosphorylation site of S75.

亚型

IgG

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anti-Proto-oncogene tyrosine-protein kinase Src (Src) (AA 1-80) antibody
Src 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

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anti-Proto-oncogene tyrosine-protein kinase Src (Src) antibody
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Src 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Proto-oncogene tyrosine-protein kinase Src (Src) (AA 24-52) antibody
Src 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-Proto-oncogene tyrosine-protein kinase Src (Src) (pTyr529) antibody
Src 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Proto-oncogene tyrosine-protein kinase Src (Src) antibody
Src 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000

说明

Expressed ubiquitously. Platelets, neurons and osteoclasts express 5-fold to 200-fold higher levels than most other tissues.

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C, and avoid repeat freeze-thaw cycles.
抗原

Src (Proto-oncogene tyrosine-protein kinase Src (Src))

别名

c-Src (Src 产品)

别名

AW259666 antibody, pp60c-src antibody, C-src1 antibody, CG7524 antibody, D-Src64B antibody, D-src antibody, DSRC64 antibody, DSrc antibody, DSrc64 antibody, DSrc64B antibody, Dm SRC1 antibody, DmHD-358 antibody, Dmel\CG7524 antibody, Dsrc antibody, Dsrc64 antibody, Dsrc64B antibody, HD-358 antibody, MRE5 antibody, SRC 64B antibody, Src antibody, Src1 antibody, Src64 antibody, c-src antibody, dSrc antibody, dsrc antibody, src antibody, src1 antibody, src64 antibody, src64B antibody, src64b antibody, ASV antibody, SRC1 antibody, c-SRC antibody, p60-Src antibody, c-Src antibody, PP60C-SCR antibody, SDR antibody, SRC proto-oncogene, non-receptor tyrosine kinase antibody, uncharacterized LOC5574802 antibody, proto-oncogene tyrosine-protein kinase src antibody, Rous sarcoma oncogene antibody, Src oncogene at 64B antibody, SRC antibody, LOC5574802 antibody, CpipJ_CPIJ010659 antibody, Src antibody, Src64B antibody

物质类

Viral Protein

分子量

60 kDa

基因ID

6714

UniProt

P12931

途径

JAK/STAT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling