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Src 抗体 (AA 24-52)

Name: Src 抗体 (AA 24-52)
SKU: ABIN3029554
Availability: OutOfStock

Src 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated

Src antibody western blot analysis in (1) MCF-7 and (2) A431 lysate (Src 抗体 (AA 24-52))

Confocal immunofluorescent analysis of Src antibody with MCF-7 cells followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (Src 抗体 (AA 24-52))

Src antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue (Src 抗体 (AA 24-52))

IHC

Src antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human small intestine tissue (Src 抗体 (AA 24-52))

IHC

Confocal immunofluorescent analysis of Src antibody with A431 cells followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (Src 抗体 (AA 24-52))

IHC

Src antibody flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control (left histogram). (Src 抗体 (AA 24-52))

FACS

10 images

产品编号 ABIN3029554

发货至: 中国

Datasheet as PDF

抗原 See all Src 抗体

Src (Proto-oncogene tyrosine-protein kinase Src (Src))
抗原表位
28

25

21

20

19

18

14

14

11

8

8

7

6

4

4

4

4

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 24-52
适用
225

143

120

9

7

7

5

5

5

4

3

2

1

1

1
人
宿主
238

19

1
兔
Compatible Secondaries
克隆类型
216

42
多克隆
标记
123

21

18

16

12

11

6

6

6

6

6

6

4

4

4

4

4

1
This Src antibody is un-conjugated
应用范围
192

133

62

55

53

35

29

29

23

12

9

7

4

3

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

交叉反应（详细）

Expected species reactivity: Mouse

纯化方法

Antigen affinity purified

免疫原

A portion of amino acids 24-52 from the human protein was used as the immunogen for this Src antibody.

亚型

Ig Fraction

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anti-Proto-oncogene tyrosine-protein kinase Src (Src) antibody
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anti-Proto-oncogene tyrosine-protein kinase Src (Src) (AA 397-424) antibody
Src 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Proto-oncogene tyrosine-protein kinase Src (Src) (pTyr529) antibody
Src 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Proto-oncogene tyrosine-protein kinase Src (Src) antibody
Src 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

anti-Proto-oncogene tyrosine-protein kinase Src (Src) (Tyr1172) antibody
Src 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Titration of the Src antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000,IHC (Paraffin): 1:50,Flow Cytometry: 1:50,Immunofluorescence: 1:50

限制

仅限研究用
状态

Liquid

缓冲液

In 1X PBS, pH 7.4, with 0.09 % sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Aliquot the Src antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
抗原

Src (Proto-oncogene tyrosine-protein kinase Src (Src))

别名

Src (Src 产品)

别名

AW259666 antibody, pp60c-src antibody, C-src1 antibody, CG7524 antibody, D-Src64B antibody, D-src antibody, DSRC64 antibody, DSrc antibody, DSrc64 antibody, DSrc64B antibody, Dm SRC1 antibody, DmHD-358 antibody, Dmel\CG7524 antibody, Dsrc antibody, Dsrc64 antibody, Dsrc64B antibody, HD-358 antibody, MRE5 antibody, SRC 64B antibody, Src antibody, Src1 antibody, Src64 antibody, c-src antibody, dSrc antibody, dsrc antibody, src antibody, src1 antibody, src64 antibody, src64B antibody, src64b antibody, ASV antibody, SRC1 antibody, c-SRC antibody, p60-Src antibody, c-Src antibody, PP60C-SCR antibody, SDR antibody, SRC proto-oncogene, non-receptor tyrosine kinase antibody, uncharacterized LOC5574802 antibody, proto-oncogene tyrosine-protein kinase src antibody, Rous sarcoma oncogene antibody, Src oncogene at 64B antibody, SRC antibody, LOC5574802 antibody, CpipJ_CPIJ010659 antibody, Src antibody, Src64B antibody

物质类

Viral Protein

背景

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-Src kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

UniProt

P12931

途径

JAK/STAT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling