DR4 抗体
(1 reference)-
- 抗原 See all DR4 抗体
- DR4 (Drought-Repressed 4 Protein (DR4))
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DR4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- TR10A antibody detects endogenous levels of total TR10A
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human TR10A
- 亚型
- IgG
- Top Product
- Discover our top product DR4 Primary Antibody
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anti-Drought-Repressed 4 Protein (DR4) (AA 401-468) antibody
DR4 适用: 人, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Drought-Repressed 4 Protein (DR4) (AA 370-450) antibodyDR4 适用: 人, 猴 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Drought-Repressed 4 Protein (DR4) (C-Term) antibodyDR4 适用: 人, 猴 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500~1:3000, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
- 有效期
- 12 months
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: "Sphingomyelin synthase 2 overexpression promotes cisplatin-induced apoptosis of HepG2 cells." in: Oncology letters, Vol. 15, Issue 1, pp. 483-488, (2018) (PubMed).
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: "Sphingomyelin synthase 2 overexpression promotes cisplatin-induced apoptosis of HepG2 cells." in: Oncology letters, Vol. 15, Issue 1, pp. 483-488, (2018) (PubMed).
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- 抗原
- DR4 (Drought-Repressed 4 Protein (DR4))
- 别名
- TR10A (DR4 产品)
- 别名
- APO2 antibody, CD261 antibody, DR4 antibody, TRAILR-1 antibody, TRAILR1 antibody, TNF receptor superfamily member 10a antibody, TNFRSF10A antibody
- 背景
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Description: Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:26457518). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.
Gene: TNFRSF10A
- 分子量
- 50kDa
- 基因ID
- 8797
- UniProt
- O00220
- 途径
- Apoptosis, Positive Regulation of Endopeptidase Activity
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