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TFAM 抗体 (Internal Region)

TFAM 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6265530
发货至: 中国
  • 抗原 See all TFAM 抗体
    TFAM (Transcription Factor A, Mitochondrial (TFAM))
    抗原表位
    • 15
    • 13
    • 9
    • 7
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 59
    • 30
    • 26
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 88
    • 4
    克隆类型
    • 80
    • 12
    多克隆
    标记
    • 41
    • 11
    • 9
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This TFAM antibody is un-conjugated
    应用范围
    • 72
    • 38
    • 28
    • 26
    • 18
    • 15
    • 14
    • 14
    • 14
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    TFAM Antibody detects endogenous levels of total TFAM.
    预测反应
    Pig,Bovine
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human TFAM, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product TFAM Primary Antibody
  • 应用备注
    IHC 1:50-1:200, IF/ICC 1:100-1:500, WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    TFAM (Transcription Factor A, Mitochondrial (TFAM))
    别名
    TFAM (TFAM 产品)
    别名
    tcf6 antibody, mttf1 antibody, mttfa antibody, tcf6l1 antibody, tcf6l2 antibody, tcf6l3 antibody, mttfa-A antibody, xl-mtTFA antibody, MGC153358 antibody, zgc:153358 antibody, MTTF1 antibody, MTTFA antibody, TCF6 antibody, TCF6L1 antibody, TCF6L2 antibody, TCF6L3 antibody, AI661103 antibody, Hmgts antibody, mtTFA antibody, tsHMG antibody, Mttfa antibody, transcription factor A, mitochondrial antibody, transcription factor A, mitochondrial L homeolog antibody, TFAM antibody, tfam.L antibody, tfam antibody, Tfam antibody
    背景

    Description: Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation (PubMed:29445193). Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA.

    Gene: TFAM

    分子量
    29kDa
    基因ID
    7019
    UniProt
    Q00059
    途径
    Chromatin Binding
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