SIGMAR1 抗体 (Internal Region)
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- 抗原 See all SIGMAR1 抗体
- SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))
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抗原表位
- Internal Region
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SIGMAR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- SIGMAR1 Antibody detects endogenous levels of total SIGMAR1.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human SIGMAR1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product SIGMAR1 Primary Antibody
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anti-sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1) antibody
SIGMAR1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1) antibodySIGMAR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1) (AA 47-81), (N-Term) antibodySIGMAR1 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB14256 unconjugated
anti-sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1) (AA 21-120) antibodySIGMAR1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1) (AA 112-169) antibodySIGMAR1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1) (AA 31-80) antibodySIGMAR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1) (AA 118-147) antibodySIGMAR1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB14335 unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:50-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))
- 别名
- SIGMAR1 (SIGMAR1 产品)
- 别名
- ALS16 antibody, OPRS1 antibody, SIG-1R antibody, SR-BP antibody, SR-BP1 antibody, SRBP antibody, sigma1R antibody, AL024364 antibody, Oprs1 antibody, mSigmaR1 antibody, Sigma1R antibody, oprs1 antibody, zgc:56378 antibody, sigma non-opioid intracellular receptor 1 antibody, sigma non-opioid intracellular receptor 1 L homeolog antibody, SIGMAR1 antibody, Sigmar1 antibody, sigmar1.L antibody, sigmar1 antibody
- 背景
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Description: Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Involved in the regulation of different receptors it plays a role in BDNF signaling and EGF signaling. Also regulates ion channels like the potassium channel and could modulate neurotransmitter release. Plays a role in calcium signaling through modulation together with ANK2 of the ITP3R-dependent calcium efflux at the endoplasmic reticulum. Plays a role in several other cell functions including proliferation, survival and death. Originally identified for its ability to bind various psychoactive drugs it is involved in learning processes, memory and mood alteration (PubMed:16472803, PubMed:9341151). Necessary for proper mitochondrial axonal transport in motor neurons, in particular the retrograde movement of mitochondria. Plays a role in protecting cells against oxidative stress-induced cell death via its interaction with RNF112 (By similarity).
Gene: SIGMAR1
- 分子量
- 25kDa
- 基因ID
- 10280
- UniProt
- Q99720
- 途径
- SARS-CoV-2 Protein Interactome
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