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FIP200 抗体

RB1CC1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6264659
发货至: 中国
  • 抗原 See all FIP200 (RB1CC1) 抗体
    FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))
    适用
    • 28
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    人, 小鼠, 大鼠
    宿主
    • 54
    • 2
    克隆类型
    • 54
    • 2
    多克隆
    标记
    • 20
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    This FIP200 antibody is un-conjugated
    应用范围
    • 35
    • 29
    • 13
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    • 6
    • 5
    • 4
    • 4
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    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    RB1CC1 antibody detects endogenous levels of RB1CC1.
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human RB1CC1.
    亚型
    IgG
    Top Product
    Discover our top product RB1CC1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C.Stable for 12 months from date of receipt
    有效期
    12 months
  • 抗原
    FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))
    别名
    RB1CC1 (RB1CC1 产品)
    别名
    DKFZp459E2330 antibody, CC1 antibody, FIP200 antibody, 2900055E04Rik antibody, 5930404L04Rik antibody, Cc1 antibody, LaXp180 antibody, RB1 inducible coiled-coil 1 antibody, RB1 inducible coiled-coil 1 L homeolog antibody, RB1-inducible coiled-coil 1 antibody, RB1CC1 antibody, rb1cc1.L antibody, rb1cc1 antibody, Rb1cc1 antibody
    背景

    Description: Involved in autophagy (PubMed:21775823). Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1 (PubMed:23392225). Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) during S.typhimurium infection and subsequent xenophagy (By similarity). Involved in repair of DNA damage caused by ionizing radiation, which subsequently improves cell survival by decreasing apoptosis (By similarity). Inhibits PTK2/FAK1 and PTK2B/PYK2 kinase activity, affecting their downstream signaling pathways (PubMed:10769033, PubMed:12221124). Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111 (By similarity). Functions as a DNA-binding transcription factor (PubMed:12095676). Is a potent regulator of the RB1 pathway through induction of RB1 expression (PubMed:14533007). Plays a crucial role in muscular differentiation (PubMed:12163359). Plays an indispensable role in fetal hematopoiesis and in the regulation of neuronal homeostasis (By similarity).

    Gene: RB1CC1

    分子量
    200 kDa
    基因ID
    9821
    UniProt
    Q8TDY2
    途径
    Regulation of Cell Size, Autophagy
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