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FIP200 抗体 (AA 1544-1594)

RB1CC1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7167417
发货至: 中国
  • 抗原 See all FIP200 (RB1CC1) 抗体
    FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))
    抗原表位
    • 15
    • 11
    • 11
    • 8
    • 7
    • 6
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 1544-1594
    适用
    • 27
    • 21
    • 16
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    宿主
    • 53
    • 2
    克隆类型
    • 53
    • 2
    多克隆
    标记
    • 19
    • 6
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FIP200 antibody is un-conjugated
    应用范围
    • 35
    • 28
    • 13
    • 13
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    ELISA, Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human RB1-inducible coiled-coil protein 1 protein (1544-1594AA)
    亚型
    IgG
    Top Product
    Discover our top product RB1CC1 Primary Antibody
  • 应用备注
    Recommended dilution: IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))
    别名
    RB1CC1 (RB1CC1 产品)
    别名
    DKFZp459E2330 antibody, CC1 antibody, FIP200 antibody, 2900055E04Rik antibody, 5930404L04Rik antibody, Cc1 antibody, LaXp180 antibody, RB1 inducible coiled-coil 1 antibody, RB1 inducible coiled-coil 1 L homeolog antibody, RB1-inducible coiled-coil 1 antibody, RB1CC1 antibody, rb1cc1.L antibody, rb1cc1 antibody, Rb1cc1 antibody
    背景

    Background: Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111. Involved in autophagy. Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1. Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) duting S.typhimurium infection and subsequent xenophagy. Autophagy positively regulates repair of DNA damage induced by ionizing radiation and negatively regulates apoptosis. Plays an indispensible role in fetal hematopoiesis and in the regulation of neuronal homeostasis (By similarity). Implicated in the regulation of RB1 expression. Functions as a DNA-binding transcription factor. Is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. Expression is, thus, a prerequisite for myogenic differentiation. Inhibits PTK2/FAK1 and PTK2B/PYK2 activity and activation of downstream signaling pathways.

    Aliases: FAK family kinase-interacting protein of 200 kDa antibody, FIP200 antibody, RB1-inducible coiled-coil protein 1 antibody, RB1CC1 antibody, RBCC1_HUMAN antibody

    UniProt
    Q8TDY2
    途径
    Regulation of Cell Size, Autophagy
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