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PPARG 抗体 (Internal Region)

PPARG 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6269231
发货至: 中国
  • 抗原 See all PPARG 抗体
    PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))
    抗原表位
    • 21
    • 18
    • 16
    • 16
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    • 14
    • 9
    • 5
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    Internal Region
    适用
    • 157
    • 109
    • 96
    • 34
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    人, 小鼠, 大鼠
    宿主
    • 149
    • 18
    • 3
    • 2
    克隆类型
    • 153
    • 20
    多克隆
    标记
    • 86
    • 14
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    • 7
    • 5
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    This PPARG antibody is un-conjugated
    应用范围
    • 155
    • 60
    • 55
    • 52
    • 52
    • 31
    • 22
    • 16
    • 14
    • 13
    • 7
    • 5
    • 5
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    PPAR gamma Antibody detects endogenous levels of total PPAR gamma.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human PPAR gamma, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product PPARG Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • Song, Zhou, Peng, Tao, Yang, Xu, Peng, Ren, Xiang, Wei: "GPR120 promotes adipogenesis through intracellular calcium and extracellular signal-regulated kinase 1/2 signal pathway." in: Molecular and cellular endocrinology, Vol. 434, pp. 1-13, (2017) (PubMed).

    Hu, Luo, Peng, Song, Zhou, Wei, Peng, Jiang: "Molecular cloning, expression pattern analysis of porcine Rb1 gene and its regulatory roles during primary dedifferentiated fat cells adipogenic differentiation." in: General and comparative endocrinology, Vol. 214, pp. 77-86, (2015) (PubMed).

  • 抗原
    PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))
    别名
    PPARG (PPARG 产品)
    别名
    PPAR gamma antibody, PPARg2 antibody, PPARG antibody, Nr1c3 antibody, PPAR-gamma antibody, PPAR-gamma2 antibody, PPARgamma antibody, PPARgamma2 antibody, NR1C3 antibody, CIMT1 antibody, GLM1 antibody, PPARG1 antibody, PPARG2 antibody, xPPAR-gamma antibody, PPAR-GAMMA antibody, PPARGAMMA antibody, peroxisome proliferator-activated receptor gamma antibody, peroxisome proliferator activated receptor gamma antibody, peroxisome proliferator activated receptor gamma L homeolog antibody, PPARG antibody, Pparg antibody, pparg.L antibody
    背景

    Description: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses. Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of ARNTL/BMAL1 in the blood vessels (By similarity).

    Gene: PPARG

    分子量
    57kDa
    基因ID
    5468
    UniProt
    P37231
    途径
    MAPK Pathway, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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