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MCM2 抗体 (N-Term)

This anti-MCM2 antibody is a 兔 多克隆 antibody detecting MCM2 in WB, IHC, ELISA, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6263158
发货至: 中国

Quick Overview for MCM2 抗体 (N-Term) (ABIN6263158)

抗原

See all MCM2 抗体
MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This MCM2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    N-Term

    特异性

    MCM2 Antibody detects endogenous levels of total MCM2.

    预测反应

    Pig,Horse,Rabbit,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human MCM2, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC: 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

    别名

    MCM2

    背景

    Description: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division. Plays a role in terminally differentiated hair cells development of the cochlea and induces cells apoptosis.

    Gene: MCM2

    分子量

    120kDa

    基因ID

    4171

    UniProt

    P49736

    途径

    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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