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GZMA 抗体 (Internal Region)

GZMA 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6262134
发货至: 中国
  • 抗原 See all GZMA 抗体
    GZMA (Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA))
    抗原表位
    • 15
    • 8
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    • 2
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    • 1
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    • 1
    Internal Region
    适用
    • 39
    • 28
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    宿主
    • 39
    • 6
    • 3
    克隆类型
    • 42
    • 6
    多克隆
    标记
    • 27
    • 5
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    • 1
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    This GZMA antibody is un-conjugated
    应用范围
    • 31
    • 19
    • 13
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    • 6
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    Western Blotting (WB), ELISA
    特异性
    GZMA Antibody detects endogenous levels of total GZMA.
    预测反应
    Horse,Dog,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human GZMA, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product GZMA Primary Antibody
  • 应用备注
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    GZMA (Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA))
    别名
    GZMA (GZMA 产品)
    别名
    gzmA antibody, GZMA antibody, AW494114 antibody, Ctla-3 antibody, Ctla3 antibody, Hf antibody, SE1 antibody, TSP-1 antibody, TSP1 antibody, CTLA3 antibody, HFSP antibody, granzyme A antibody, Granzyme A antibody, granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) antibody, gzmA antibody, GZMA antibody, graa antibody, Gzma antibody
    背景

    Description: Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA.

    Gene: GZMA

    分子量
    28 kDa
    基因ID
    3001
    UniProt
    P12544
    途径
    Apoptosis
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