GZMA 产品
(Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA))
Categories
Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. [provided by RefSeq, Jul 2008].
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Featured GZMA Categories
GZMA 抗体
High quality antibodies with extensive validation data.
GZMA ELISA试剂盒
Reliable ELISA kits for a wide range of species.
GZMA 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GZMA 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7440233
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IP, FACS, ICC
Validations
- (2)
Cat. No.
ABIN7505978
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN6141551
Quantity
100 μL
Datasheet
Datasheet
Recommended GZMA ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6956296
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956297
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6999395
Quantity
96 tests
Datasheet
Datasheet
Recommended GZMA 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123196
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306257
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306259
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our GZMA Products
: "Extracellular granzyme A in amniotic fluid is elevated in the presence of sterile intra-amniotic inflammation in preterm prelabor rupture of membranes." in: The journal of maternal-fetal & neonatal medicine, pp. 1-10, (2020) (PubMed).: "CXCR5+CD8+ T cells present elevated capacity in mediating cytotoxicity toward autologous tumor cells through interleukin 10 in diffuse large B-cell lymphoma." in: International immunopharmacology, Vol. 50, pp. 146-151, (2018) (PubMed).
: "Exposure to particulate matter 2.5 (PM2.5) induced macrophage-dependent inflammation, characterized by increased Th1/Th17 cytokine secretion and cytotoxicity." in: International immunopharmacology, Vol. 50, pp. 139-145, (2018) (PubMed).
: "Interleukin 10 enhanced CD8+ T cell activity and reduced CD8+ T cell apoptosis in patients with diffuse large B cell lymphoma." in: Experimental cell research, Vol. 360, Issue 2, pp. 146-152, (2017) (PubMed).
: "Relationships among plasma granzyme B level, pruritus and dermatitis in patients with atopic dermatitis." in: Journal of dermatological science, Vol. 84, Issue 3, pp. 266-271, (2016) (PubMed).
: "MAIT cells are licensed through granzyme exchange to kill bacterially sensitized targets." in: Mucosal immunology, Vol. 8, Issue 2, pp. 429-40, (2015) (PubMed).
: "Granzyme A produces bioactive IL-1? through a nonapoptotic inflammasome-independent pathway." in: Cell reports, Vol. 9, Issue 3, pp. 910-7, (2014) (PubMed).
: "Thalidomide maintenance therapy maturates the T cell compartment and compromises antigen-specific antitumor immunity in patients with multiple myeloma." in: Experimental hematology, Vol. 41, Issue 3, pp. 231-40, (2013) (PubMed).
: "The IL-7Rα pathway is quantitatively and functionally altered in CD8 T cells in multiple sclerosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 4, pp. 1874-83, (2012) (PubMed).
: "Proteolytic activation of the cytotoxic phenotype during human NK cell development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 2, pp. 803-13, (2009) (PubMed).
Synonyms and alternative names related to GZMA
granzyme A (gzmA), granzyme A (GZMA), Granzyme A (graa), granzyme A (Gzma), granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) (GZMA), AW494114, Ctla-3, Ctla3, CTLA3, gzmA, GZMA, Hf, HFSP, SE1, TSP-1, TSP1Protein level used designations for GZMA
- granzyme A
- Granzyme A
- BLT esterase
- H factor
- Hanukah factor
- autocrine thymic lymphoma granzyme-like serine protease
- fragmentin-1
- serine esterase 1
- t cell-specific serine protease 1
- CTL tryptase
- Granzyme A (Cytotoxic T-lymphocyte-associated serine esterase-3; Hanukah factor serine protease)
- HF
- cytotoxic T-lymphocyte proteinase 1
- h factor
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