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H13 产品

(Histocompatibility 13 (H13))

Categories

The protein encoded by this gene, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. The encoded protein is an integral membrane protein with sequence motifs characteristic of the presenilin-type aspartic proteases. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured H13 Categories

H13 抗体

High quality antibodies with extensive validation data.

H13 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended H13 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
  • (2)
Cat. No. ABIN1387572
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (2)
Cat. No. ABIN7159822
Quantity 100 μg
Datasheet Datasheet
Reactivity Chicken, Cow, Human, Mouse, Pig, Rabbit, Rat, Xenopus laevis
Application WB
Validations
  • (1)
Cat. No. ABIN6746312
Quantity 100 μL
Datasheet Datasheet

Recommended H13 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306780
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3116824
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3129341
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our H13 Products

Makowski, Wang, Pomerantz: "A protease-independent function for SPPL3 in NFAT activation." in: Molecular and cellular biology, Vol. 35, Issue 2, pp. 451-67, (2014) (PubMed).

Nyborg, Kornilova, Jansen, Ladd, Wolfe, Golde: "Signal peptide peptidase forms a homodimer that is labeled by an active site-directed gamma-secretase inhibitor." in: The Journal of biological chemistry, Vol. 279, Issue 15, pp. 15153-60, (2004) (PubMed).

Friedmann, Lemberg, Weihofen, Dev, Dengler, Rovelli, Martoglio: "Consensus analysis of signal peptide peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared with presenilins." in: The Journal of biological chemistry, Vol. 279, Issue 49, pp. 50790-8, (2004) (PubMed).

Urny, Hermans-Borgmeyer, Gercken, Schaller: "Expression of the presenilin-like signal peptide peptidase (SPP) in mouse adult brain and during development." in: Gene expression patterns : GEP, Vol. 3, Issue 5, pp. 685-91, (2003) (PubMed).

Synonyms and alternative names related to H13

histocompatibility minor 13 (HM13), histocompatibility (minor) 13 (hm13), histocompatibility (minor) 13 L homeolog (hm13.L), histocompatibility 13 (H13), histocompatibility minor 13 (Hm13), 1200006O09Rik, 4930443L17Rik, 5031424B04Rik, AV020344, cb228, dJ324O17.1, H-13, H13, h13, Hm13, IMP1, IMPAS, IMPAS-1, MGC68919, MSTP086, PSENL3, PSL3, SPP, Spp, SPPL1, wu:fc11a06, zgc:56660, zgc:86862

Protein level used designations for H13

  • IMP-1
  • hIMP1
  • intramembrane protease 1
  • minor histocompatibility antigen 13
  • minor histocompatibility antigen H13
  • presenilin-like protein 3
  • signal peptide peptidase beta
  • signal peptide peptidase like 1
  • histocompatibility 13
  • signal peptide peptidase
  • intramembrane aspartyl protease
  • histocompatibility (minor) 13
  • presenilin-like aspartyl protease
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