电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

GZMB 产品

(Granzyme B (GZMB))

Categories

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq, Jul 2008].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured GZMB Categories

GZMB 抗体

High quality antibodies with extensive validation data.

GZMB ELISA试剂盒

Reliable ELISA kits for a wide range of species.

GZMB 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GZMB 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7432145
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, StM
Validations
  • (5)
Cat. No. ABIN6939591
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro)
Validations
  • (1)
  • (3)
Cat. No. ABIN675354
Quantity 100 μL
Datasheet Datasheet

Recommended GZMB ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6956298
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6956299
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6956300
Quantity 96 tests
Datasheet Datasheet

Recommended GZMB 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306262
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306264
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320540
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our GZMB Products

Islimye Taskin, Guney, Adali, Hismiogullari, Dodurga, Elmas: "Granzyme B levels and granzyme B polymorphisms in peripheral blood of patients with endometriosis: a preliminary study." in: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, Vol. 41, Issue 1, pp. 94-99, (2021) (PubMed).

Qian, Shi, Qi, Zhao, Huang, Han, Zhou, Liu, Liu, Lu, Yuan, Zhao, Kang: "A novel Granzyme B nanoparticle delivery system simulates immune cell functions for suppression of solid tumors." in: Theranostics, Vol. 9, Issue 25, pp. 7616-7627, (2020) (PubMed).

Baumann, Dunkel, Schmid, Schmitt, Hiltensperger, Lohr, Laketa, Donakonda, Ahting, Lorenz-Depiereux, Heil, Schredelseker, Simeoni, Fecher, Körber, Bauer, Hüser, Hartmann, Laschinger, Eyerich, Eyerich et al.: "Regulatory myeloid cells paralyze T cells through cell-cell transfer of the metabolite methylglyoxal. ..." in: Nature immunology, Vol. 21, Issue 5, pp. 555-566, (2020) (PubMed).

Bengsch, Ohtani, Khan, Setty, Manne, OBrien, Gherardini, Herati, Huang, Chang, Newell, Bovenschen, Peer, Albelda, Wherry: "Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T Cells." in: Immunity, Vol. 48, Issue 5, pp. 1029-1045.e5, (2019) (PubMed).

Park, Shin, Kim, Bilsborrow, Mohanty, Montgomery, Shaw, You, Kang: "Transcriptomic analysis of human IL-7 receptor alpha low and high effector memory CD8+ T cells reveals an age-associated signature linked to influenza vaccine response in older adults." in: Aging cell, Vol. 18, Issue 4, pp. e12960, (2019) (PubMed).

Paidipally, Tripathi, Van, Radhakrishnan, Dhiman, Venkatasubramanian, Devalraju, Tvinnereim, Valluri, Vankayalapati: "Interleukin-21 Regulates Natural Killer Cell Responses During Mycobacterium tuberculosis Infection." in: The Journal of infectious diseases, Vol. 217, Issue 8, pp. 1323-1333, (2019) (PubMed).

Giles, Hao, Padget, Song, Zhang, Lynes, Sanchez, Liu, Jung, Cao, Fujii, Jensen, Gillespie, Schlom, Gilbert, Nduom, Yang, Lee, Soon-Shiong, Hodge, Park: "Efficient ADCC killing of meningioma by avelumab and a high-affinity natural killer cell line, haNK." in: JCI insight, Vol. 4, Issue 20, (2019) (PubMed).

Ouni, Gharsalli, Dirix, Braiek, Sendi, Jarraya, Douik El Gharbi, Barbouche, Benabdessalem: "Granzyme B induced by Rv0140 antigen discriminates latently infected from active tuberculosis individuals." in: Journal of leukocyte biology, Vol. 105, Issue 2, pp. 297-306, (2019) (PubMed).

Gatault, Al-Hajj, Noble, Chevallier, Piollet, Forconi, Gaudy-Graffin, Thibault, Miquelestorena-Standley, Halimi, Büchler, Lemoine, Baron: "CMV-infected kidney grafts drive the expansion of blood-borne CMV-specific T cells restricted by shared class I HLA molecules via presentation on donor cells." in: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, Vol. 18, Issue 8, pp. 1904-1913, (2019) (PubMed).

Hartana, Ahlén Bergman, Zirakzadeh, Krantz, Winerdal, Winerdal, Johansson, Alamdari, Jakubczyk, Glise, Riklund, Sherif, Winqvist: "Urothelial bladder cancer may suppress perforin expression in CD8+ T cells by an ICAM-1/TGFβ2 mediated pathway." in: PLoS ONE, Vol. 13, Issue 7, pp. e0200079, (2019) (PubMed).

Synonyms and alternative names related to GZMB

granzyme B (GZMB), CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT

Protein level used designations for GZMB

  • C11
  • CTLA-1
  • T-cell serine protease 1-3E
  • cathepsin G-like 1
  • cytotoxic T-lymphocyte proteinase 2
  • cytotoxic serine protease B
  • fragmentin 2
  • fragmentin-2
  • granzyme B
  • human lymphocyte protein
You are here:
客服