H2AFB3 产品
(H2A Histone Family, Member B3 (H2AFB3))
Categories
Atypical histone H2A which can replace conventional H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Nucleosomes containing this histone are less rigid and organize only 118 base pair of DNA instead of 147 in classical nucleosomes. They are associated with transcriptionally active chromatin and excluded form Barr bodies.
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Recommended H2AFB3 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (1)
Cat. No.
ABIN566514
Quantity
50 μL
Datasheet
Datasheet
Recommended H2AFB3 蛋白
Synonyms and alternative names related to H2AFB3
H2A histone family member B3 (H2AFB3), H2A histone family, member B3 (H2afb3), H2A histone family, member B3 (H2AFB3), EG624957, H2A.Bbd3, H2ABBD, H2AFB, H2afb3, RGD1561666Protein level used designations for H2AFB3
- H2A Barr body-deficient
- H2A.Bbd
- histone H2A-Bbd type 2/3
- histone variant H2A, Barr-body deficient
- H2A histone family, member B3
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