ABI1 抗体 (Internal Region)
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- 抗原 See all ABI1 抗体
- ABI1 (Abl-Interactor 1 (ABI1))
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抗原表位
- Internal Region
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ABI1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- Abi 1 Antibody detects endogenous levels of total Abi 1.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human Abi 1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product ABI1 Primary Antibody
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anti-Abl-Interactor 1 (ABI1) (AA 1-182) antibody
ABI1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Abl-Interactor 1 (ABI1) (AA 180-230) antibodyABI1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Abl-Interactor 1 (ABI1) (AA 151-175), (N-Term) antibodyABI1 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Abl-Interactor 1 (ABI1) antibodyABI1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Abl-Interactor 1 (ABI1) (C-Term) antibodyABI1 适用: 人, 大鼠, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Abl-Interactor 1 (ABI1) (AA 483-494), (C-Term) antibodyABI1 适用: 人, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Abl-Interactor 1 (ABI1) (AA 81-108), (N-Term) antibodyABI1 适用: 人 WB, IHC (p), IF, FACS 宿主: 兔 Polyclonal RB22014 unconjugated
anti-Abl-Interactor 1 (ABI1) antibodyABI1 适用: 人, 大鼠, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Abl-Interactor 1 (ABI1) (AA 87-117), (N-Term) antibodyABI1 适用: 人 WB, IHC (p), IF, FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Abl-Interactor 1 (ABI1) (AA 81-108) antibodyABI1 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- ABI1 (Abl-Interactor 1 (ABI1))
- 别名
- ABI1 (ABI1 产品)
- 别名
- ABI-1 antibody, ABLBP4 antibody, E3B1 antibody, NAP1BP antibody, SSH3BP antibody, SSH3BP1 antibody, NAP1 antibody, Ssh3bp1 antibody, E3b1 antibody, abi1 antibody, wu:fc66g09 antibody, wu:fk56a10 antibody, zgc:73174 antibody, MGC84356 antibody, ABI1 antibody, abi-1 antibody, e3b1 antibody, nap1bp antibody, ssh3bp antibody, ssh3bp1 antibody, wu:fe48a10 antibody, zgc:153534 antibody, DKFZp469P1319 antibody, abl interactor 1 antibody, abl-interactor 1 antibody, abl-interactor 1a antibody, abl interactor 1 S homeolog antibody, abl-interactor 1b antibody, Abl-interactor 1 antibody, Abl interactor 1 antibody, ABI1 antibody, Abi1 antibody, abi1a antibody, abi1.S antibody, abi1 antibody, abi1b antibody, Bm1_44660 antibody, LOAG_04356 antibody
- 背景
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Description: May act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. May play a role in regulation of EGF-induced Erk pathway activation. Involved in cytoskeletal reorganization and EGFR signaling. Together with EPS8 participates in transduction of signals from Ras to Rac. In vitro, a trimeric complex of ABI1, EPS8 and SOS1 exhibits Rac specific guanine nucleotide exchange factor (GEF) activity and ABI1 seems to act as an adapter in the complex. Regulates ABL1/c-Abl-mediated phosphorylation of ENAH. Recruits WASF1 to lamellipodia and there seems to regulate WASF1 protein level. In brain, seems to regulate the dendritic outgrowth and branching as well as to determine the shape and number of synaptic contacts of developing neurons.
Gene: ABI1
- 分子量
- 55 kDa
- 基因ID
- 10006
- UniProt
- Q8IZP0
- 途径
- RTK signaling, Response to Water Deprivation, ER-Nucleus Signaling
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