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ABI1 抗体 (C-Term)

ABI1 适用: 人, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043678
发货至: 中国
  • 抗原 See all ABI1 抗体
    ABI1 (Abl-Interactor 1 (ABI1))
    抗原表位
    • 15
    • 12
    • 11
    • 8
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 483-494, C-Term
    适用
    • 62
    • 45
    • 37
    • 9
    • 9
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    人, 大鼠
    宿主
    • 76
    • 3
    克隆类型
    • 76
    • 3
    多克隆
    标记
    • 44
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ABI1 antibody is un-conjugated
    应用范围
    • 60
    • 23
    • 15
    • 15
    • 14
    • 13
    • 13
    • 8
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    原理
    Rabbit IgG polyclonal antibody for Abl interactor 1(ABI1) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
    序列
    WYEGVCNRVT GL
    交叉反应 (详细)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for Abl interactor 1(ABI1) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
    Gene Name: abl-interactor 1
    Protein Name: Abl interactor 1
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human ABI1(483-494aa WYEGVCNRVTGL), different from the related rat and mouse sequences by one amino acid.
    亚型
    IgG
    Top Product
    Discover our top product ABI1 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Cui, Yu, Dong, Chen, Zhang, Liu: "Downregulation of ABI1 expression affects the progression and prognosis of human gastric carcinoma." in: Medical oncology (Northwood, London, England), Vol. 27, Issue 3, pp. 632-9, (2010) (PubMed).

  • 抗原
    ABI1 (Abl-Interactor 1 (ABI1))
    别名
    ABI1 (ABI1 产品)
    别名
    ABI-1 antibody, ABLBP4 antibody, E3B1 antibody, NAP1BP antibody, SSH3BP antibody, SSH3BP1 antibody, NAP1 antibody, Ssh3bp1 antibody, E3b1 antibody, abi1 antibody, wu:fc66g09 antibody, wu:fk56a10 antibody, zgc:73174 antibody, MGC84356 antibody, ABI1 antibody, abi-1 antibody, e3b1 antibody, nap1bp antibody, ssh3bp antibody, ssh3bp1 antibody, wu:fe48a10 antibody, zgc:153534 antibody, DKFZp469P1319 antibody, abl interactor 1 antibody, abl-interactor 1 antibody, abl-interactor 1a antibody, abl interactor 1 S homeolog antibody, abl-interactor 1b antibody, Abl-interactor 1 antibody, Abl interactor 1 antibody, ABI1 antibody, Abi1 antibody, abi1a antibody, abi1.S antibody, abi1 antibody, abi1b antibody, Bm1_44660 antibody, LOAG_04356 antibody
    背景
    ABI1 is a human homolog of mouse Abl-interactor-1(Abi1), mapped on 10p11.2. ABI1 participates in the transduction of signals from Ras to Rac by regulating Rac-specific guanine nucleotide exchange factor(GEF) activities. ABI1 dramatically promoted ABL1-mediated tyrosine phosphorylation of MENA, but not of other substrates. Abi-1 regulates c-Abl-mediated phosphorylation of Mena by interacting with both proteins. ABI1 plays a role in the leukemogenesis by translocating to MLL.

    Synonyms: Abelson interactor 1 antibody|ABI 1 antibody|Abi-1 antibody|ABI1 antibody|ABI1_HUMAN antibody|Abl binding protein 4 antibody|Abl interactor 1 antibody|Abl interactor protein 1 antibody|Abl interactor protein 1 long antibody|Abl-binding protein 4 antibody|AblBP4 antibody|Ablphilin 1 antibody|E3B1 antibody|Eps8 binding protein antibody|Eps8 SH3 domain binding protein antibody|Eps8 SH3 domain-binding protein antibody|Eps8-binding protein antibody|Hssh3bp1 antibody|Interactor protein AblBP4 antibody|NAP1 antibody|Nap1 binding protein antibody|Nap1-binding protein antibody|NAP1BP antibody|Spectrin SH3 domain binding protein 1 antibody|Spectrin SH3 domain-binding protein 1 antibody|SSH3BP antibody
    途径
    RTK signaling, Response to Water Deprivation, ER-Nucleus Signaling
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