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- 抗原 See all TSEN2 抗体
- TSEN2 (tRNA-splicing Endonuclease Subunit SEN2 (TSEN2))
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抗原表位
- Internal Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TSEN2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- TSEN2 Antibody detects endogenous levels of total TSEN2.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human TSEN2, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product TSEN2 Primary Antibody
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anti-tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) antibody
TSEN2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) (AA 1-220) antibodyTSEN2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) (AA 1-465) antibodyTSEN2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) (AA 1-220) antibodyTSEN2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) antibodyTSEN2 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) (AA 395-444) antibodyTSEN2 适用: 人, 兔, 犬, 马, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) antibodyTSEN2 适用: 人 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- TSEN2 (tRNA-splicing Endonuclease Subunit SEN2 (TSEN2))
- 别名
- TSEN2 (TSEN2 产品)
- 别名
- AU067695 antibody, RGD1309946 antibody, PCH2B antibody, SEN2 antibody, SEN2L antibody, tRNA splicing endonuclease subunit 2 antibody, TSEN2 antibody, Tsen2 antibody
- 背景
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Description: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. Isoform 1 probably carries the active site for 5'-splice site cleavage. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events. Isoform 2 is responsible for processing a yet unknown RNA substrate. The complex containing isoform 2 is not able to cleave pre-tRNAs properly, although it retains endonucleolytic activity.
Gene: TSEN2
- 分子量
- 54 kDa
- 基因ID
- 80746
- UniProt
- Q8NCE0
- 途径
- Nuclear Receptor Transcription Pathway, Regulation of Lipid Metabolism by PPARalpha
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