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TSEN2 抗体 (AA 1-220)

TSEN2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7173541
发货至: 中国
  • 抗原 See all TSEN2 抗体
    TSEN2 (tRNA-splicing Endonuclease Subunit SEN2 (TSEN2))
    抗原表位
    • 14
    • 7
    • 2
    • 1
    • 1
    • 1
    AA 1-220
    适用
    • 37
    • 17
    • 17
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 35
    • 2
    克隆类型
    • 37
    多克隆
    标记
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TSEN2 antibody is un-conjugated
    应用范围
    • 36
    • 14
    • 13
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human tRNA-splicing endonuclease subunit Sen2 protein (1-220AA)
    亚型
    IgG
    Top Product
    Discover our top product TSEN2 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:200-1:1000, IHC:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    TSEN2 (tRNA-splicing Endonuclease Subunit SEN2 (TSEN2))
    别名
    TSEN2 (TSEN2 产品)
    别名
    AU067695 antibody, RGD1309946 antibody, PCH2B antibody, SEN2 antibody, SEN2L antibody, tRNA splicing endonuclease subunit 2 antibody, TSEN2 antibody, Tsen2 antibody
    背景

    Background: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5\\\'- and 3\\\'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2\\\',3\\\'-cyclic phosphate and 5\\\'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. Isoform 1 probably carries the active site for 5\\\'-splice site cleavage. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3\\\'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3\\\'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events. Isoform 2 is responsible for processing a yet unknown RNA substrate. The complex containing isoform 2 is not able to cleave pre-tRNAs properly, although it retains endonucleolytic activity.

    Aliases: HsSen2 antibody, MGC2776 antibody, MGC4440 antibody, SEN2 antibody, SEN2_HUMAN antibody, SEN2L antibody, tRNA intron endonuclease Sen2 antibody, tRNA splicing endonuclease 2 homolog (SEN2, S. cerevisiae) antibody, tRNA splicing endonuclease subunit Sen2 antibody, tRNA-intron endonuclease sen2 antibody, tRNA-splicing endonuclease subunit Sen2 antibody, TSEN 2 antibody, TSEN2 antibody

    UniProt
    Q8NCE0
    途径
    Nuclear Receptor Transcription Pathway, Regulation of Lipid Metabolism by PPARalpha
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