MARK1 抗体
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- 抗原 See all MARK1 抗体
- MARK1 (MAP/microtubule Affinity-Regulating Kinase 1 (MARK1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MARK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- MARK Antibody detects endogenous levels of total MARK
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide
- 亚型
- IgG
- Top Product
- Discover our top product MARK1 Primary Antibody
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- 应用备注
- WB 1:500~1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
- 有效期
- 12 months
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- 抗原
- MARK1 (MAP/microtubule Affinity-Regulating Kinase 1 (MARK1))
- 别名
- MARK (MARK1 产品)
- 别名
- MGC80341 antibody, MARK1 antibody, AW491150 antibody, B930025N23Rik antibody, Emk3 antibody, Par-1c antibody, mKIAA1477 antibody, mPar-1c antibody, MARK antibody, Par1c antibody, MAP/microtubule affinity-regulating kinase 1 S homeolog antibody, microtubule affinity regulating kinase 1 antibody, MAP/microtubule affinity-regulating kinase 1 antibody, MAP/microtubule affinity regulating kinase 1 antibody, mark1.S antibody, MARK1 antibody, mark1 antibody, Mark1 antibody
- 背景
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Description: Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2, MAP4 and MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).
Gene: MARK1
- 分子量
- 89 kDa
- 基因ID
- 4139
- UniProt
- Q9P0L2, Q7KZI7, P27448, Q96L34
- 途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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