LAG3 抗体 (Extracellular Domain)
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- 抗原 See all LAG3 抗体
- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
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抗原表位
- Extracellular Domain
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This LAG3 antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 纯化方法
- LAG-3 Antibody is supplied as protein A purified IgG2a.
- 免疫原
- LAG-3 antibody was raised against the extracellular domain of human LAG-3
- 克隆位点
- 9F9
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product LAG3 Primary Antibody
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anti-Lymphocyte-Activation Gene 3 (LAG3) antibody
LAG3 适用: 人 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 3A4A10 unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 103-132) antibodyLAG3 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21775 unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 103-132) antibodyLAG3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 29-450) antibodyLAG3 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 8B12E10 unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (N-Term) antibodyLAG3 适用: 人 WB, ELISA, IHC, FACS, ICC, IP 宿主: 小鼠 Monoclonal L4-PL33 unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 1-360) antibodyLAG3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 201-300) antibodyLAG3 适用: 人, 小鼠 WB, ELISA, ICC, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 244-487) antibodyLAG3 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 209-451) antibodyLAG3 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 29-450) antibodyLAG3 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- LAG-3 antibody can be used for ELISA starting at 0.25 μ,g/mL. For Immunocytochemistry start at 1 μ,g/mL. For Immunofluorescence start at 10 μ,g/mL. For Immunohistochemistry start at 5 μ,g/mL. For Flow Cytometry start at 1 μ,g/mL.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- LAG-3 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- LAG-3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
- 别名
- LAG3 (LAG3 产品)
- 别名
- CD223 antibody, LAG-3 antibody, Ly66 antibody, lymphocyte activating 3 antibody, lymphocyte-activation gene 3 antibody, LAG3 antibody, Lag3 antibody
- 背景
- The lymphocyte activation gene-3 (LAG3) is a member of the immunoglobulin superfamily and binds MHC class II with high affinity (1), negatively regulating T-cell function and homeostasis (2). It is expressed in B, T, and NK cells, monocytes, and dendritic cells (3), and acts to regulate T cell expansion (4). LAG3 is also an important immune checkpoint protein, with anti-LAG3 antibodies activating T effector cells and affecting regulatory T cell functions. Furthermore LAG3 appears to act in a synergistic fashion with PD-1/PD-L1, suggesting that a dual antibody approach may prove useful in cancer immunotherapy.
- 基因ID
- 3902
- NCBI登录号
- NP_002277
- UniProt
- P18627
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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