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LAG3 抗体 (AA 201-300)

LAG3 适用: 人, 小鼠 WB, ELISA, ICC, IHC (p), IF (p), IHC (fro), IF (cc) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN748508
发货至: 中国
  • 抗原 See all LAG3 抗体
    LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
    抗原表位
    • 14
    • 14
    • 9
    • 7
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-300
    适用
    • 87
    • 33
    • 10
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 51
    • 35
    • 7
    • 4
    克隆类型
    • 52
    • 42
    • 1
    多克隆
    标记
    • 51
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LAG3 antibody is un-conjugated
    应用范围
    • 68
    • 35
    • 30
    • 29
    • 24
    • 22
    • 14
    • 13
    • 12
    • 9
    • 9
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc))
    交叉反应
    人, 小鼠
    预测反应
    Rat,Cow,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Lymphocyte Activation Gene 3
    亚型
    IgG
    Top Product
    Discover our top product LAG3 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Chen, Huang, Lu, Wang, Chi: "Antitumor effects of the silencing of programmed cell death ligand 1 in colorectal cancer via immunoregulation." in: Oncology reports, Vol. 40, Issue 6, pp. 3370-3380, (2018) (PubMed).

    Parodi, Battaglia, Kalli, Ferrera, Conteduca, Tardito, Stringara, Ivaldi, Negrini, Borgonovo, Simonato, Traverso, Carmignani, Fenoglio, Filaci: "CD39 is highly involved in mediating the suppression activity of tumor-infiltrating CD8+ T regulatory lymphocytes." in: Cancer immunology, immunotherapy : CII, Vol. 62, Issue 5, pp. 851-62, (2013) (PubMed).

  • 抗原
    LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
    别名
    Lymphocyte Activation Gene 3 (LAG3 产品)
    别名
    CD223 antibody, LAG-3 antibody, Ly66 antibody, lymphocyte activating 3 antibody, lymphocyte-activation gene 3 antibody, LAG3 antibody, Lag3 antibody
    背景

    Synonyms: CD223, Lymphocyte activation gene 3 protein, LAG-3, Lag3

    Background: Lymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG-3 to CD4.

    基因ID
    297596
    UniProt
    Q5BK54
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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