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- 抗原 See all HIF1AN 抗体
- HIF1AN (Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN))
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抗原表位
- AA 1-349
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This HIF1AN antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- 免疫原
- This HIF1AN antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 1-349 amino acids from human HIF1AN.
- 克隆位点
- 931CT3-1-1
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product HIF1AN Primary Antibody
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anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 31-349) antibody
HIF1AN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 1-349) antibodyHIF1AN 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 1D8 unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 2-254) antibodyHIF1AN 适用: 人 WB, ELISA, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 1-349) antibodyHIF1AN 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) antibodyHIF1AN 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (N-Term) antibodyHIF1AN 适用: 人, 兔, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (C-Term) antibodyHIF1AN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (C-Term) antibodyHIF1AN 适用: 人, 小鼠, 大鼠 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) antibodyKO Validated HIF1AN 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) antibodyHIF1AN 适用: 人, 小鼠, 大鼠 WB, IHC, IP, IF, ChIP, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IF: 1:25. WB: 1:4000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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- 抗原
- HIF1AN (Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN))
- 别名
- HIF1AN (HIF1AN 产品)
- 别名
- FIH1 antibody, 2310046M24Rik antibody, A830014H24Rik antibody, cb728 antibody, id:ibd5139 antibody, hypoxia inducible factor 1 alpha subunit inhibitor antibody, hypoxia-inducible factor 1, alpha subunit inhibitor antibody, hypoxia inducible factor 1, alpha subunit inhibitor antibody, hypoxia-inducible factor 1, alpha subunit inhibitor S homeolog antibody, HIF1AN antibody, Hif1an antibody, hif1an antibody, hif1an.S antibody
- 背景
- Hydroxylates HIF-1 alpha at 'Asp-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300- interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases. Hydroxylates specific Asn residues within ankyrin repeat domains (ARD) of NFKB1, NFKBIA, NOTCH1, ASB4, PPP1R12A and several other ARD-containing proteins. Also hydroxylates Asp and His residues within ARDs of ANK1 and TNKS2, respectively. Negatively regulates NOTCH1 activity, accelerating myogenic differentiation. Positively regulates ASB4 activity, promoting vascular differentiation.
- 分子量
- 40285
- UniProt
- Q9NWT6
- 途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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