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CD4 抗体 (CF®405S)

CD4 适用: 人, Chimpanzee, Macaca arctoides, Orang-Utan FACS, IF 宿主: 小鼠 Monoclonal EDU-2 CF®405S
产品编号 ABIN6187219
发货至: 中国
  • 抗原 See all CD4 抗体
    CD4
    适用
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    人, Chimpanzee, Macaca arctoides, Orang-Utan
    宿主
    • 301
    • 144
    • 95
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD4 antibody is conjugated to CF®405S
    应用范围
    • 438
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    Flow Cytometry (FACS), Immunofluorescence (IF)
    原理
    Mouse Monoclonal anti-CD4 (EDU-2), CF405S Conjugate
    产品特性
    This antibody recognizes a protein of 55 kDa, identified as CD4. It is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.This MAb was characterized as human CD4 antibody at II and IV International Workshop on Human Leukocyte Differentiation Antigens. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    免疫原
    Stimulated human leukocytes
    克隆位点
    EDU-2
    亚型
    IgG2a kappa
    Top Product
    Discover our top product CD4 Primary Antibody
  • 应用备注
    Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Does not react with Macaca mulatta (rhesus monkey), others not tested
    • Optimal dilution for a specific application should be determined by user
    说明

    Human peripheral blood mononuclear cells (PBMCs), CCRF-CEM or HL-60. Lymph node or tonsil.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100 μg/mL
    缓冲液
    PBS/0.1 % BSA/0.05 % azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from light
  • 抗原
    CD4
    别名
    CD4 (CD4 产品)
    别名
    cd4 antibody, L3T4 antibody, Ly-4 antibody, CD4mut antibody, W3/25 antibody, p55 antibody, CD4 molecule antibody, carcinoembryonic antigen-related cell adhesion molecule 5 antibody, T-cell surface glycoprotein CD4 antibody, CD4 antigen antibody, Cd4 molecule antibody, CD4 antibody, LOC100125525 antibody, cd4 antibody, Cd4 antibody
    背景
    L3T4, Leu3, Ly-4, Lymphocyte antigen CD4, p55, T cell antigen T4/LEU3, T cell differentiation antigen L3T4, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4
    分子量
    55 kDa
    基因ID
    920, 631659
    UniProt
    P01730
    途径
    TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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