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SUMO1 抗体

SUMO1 适用: 人, 大鼠 WB, IF, FACS, IHC (f) 宿主: 小鼠 Monoclonal SUMO1-1188 unconjugated
产品编号 ABIN6186913
发货至: 中国
  • 抗原 See all SUMO1 抗体
    SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))
    适用
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    人, 大鼠
    宿主
    • 120
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    小鼠
    克隆类型
    • 115
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    单克隆
    标记
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    This SUMO1 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    原理
    Mouse Monoclonal anti-SUMO 1 (SUMO1/1188), Purified, BSA-free
    产品特性
    This MAb is specific to SUMO-1 and shows no cross-reaction with either SUMO-2 or SUMO-3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, SUMO-2 and SUMO-3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2, and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1 protein localizes to the nuclear membrane. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    纯化方法
    Purified
    免疫原
    Recombinant human SUMO1 protein
    克隆位点
    SUMO1-1188
    亚型
    IgG1 kappa
    Top Product
    Discover our top product SUMO1 Primary Antibody
  • 应用备注
    Immunohistology formalin-fixed 0.5-1 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
    • Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Western blotting 0.5-1 μg/mL
    • Predicted to show broad species reactivity
    • Optimal dilution for a specific application should be determined by user
    说明

    Breast carcinoma

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS (no BSA, no azide)
    储存液
    Azide free
  • 抗原
    SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))
    别名
    SUMO 1 (SUMO1 产品)
    别名
    DAP1 antibody, GMP1 antibody, OFC10 antibody, PIC1 antibody, SENP2 antibody, SMT3 antibody, SMT3C antibody, SMT3H3 antibody, UBL1 antibody, hm:zeh0670 antibody, wu:fb74c02 antibody, wu:fd12c02 antibody, zgc:65934 antibody, zgc:85634 antibody, SUMO1 antibody, dap1 antibody, gmp1 antibody, ofc10 antibody, pic1 antibody, senp2 antibody, smt3 antibody, smt3c antibody, sumo-1 antibody, sumo1 antibody, ubl1 antibody, xsumo-1 antibody, xsumo1 antibody, ARABIDOPSIS THALIANA SMALL UBIQUITIN-LIKE MODIFIER 1 antibody, ATSUMO1 antibody, F10M23.180 antibody, F10M23_180 antibody, SMALL UBIQUITIN-LIKE MODIFIER 1 antibody, SUM1 antibody, SUMO 1 antibody, small ubiquitin-like modifier 1 antibody, pigSUMO1 antibody, SENTRIN antibody, SMTP3 antibody, SUMO-1 antibody, Smt3C antibody, Ubl1 antibody, small ubiquitin-like modifier 1 antibody, small ubiquitin-like modifier 1 S homeolog antibody, small ubiquitin-related protein 1 antibody, SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) antibody, SMT3 suppressor of mif two 3 homolog 1 (yeast) antibody, small ubiquitin-like modifier 1 L homeolog antibody, Sumo1 antibody, SUMO1 antibody, sumo1 antibody, sumo1.S antibody, sumo-1 antibody, sumo1.L antibody
    分子量
    11.5 kDa (Monomer), 90 kDa (Heteromer)
    基因ID
    7341, 596171
    UniProt
    P63165
    途径
    M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, Ubiquitin Proteasome Pathway
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