SUMO1 抗体 (N-Term)
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- 抗原 See all SUMO1 抗体
- SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))
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抗原表位
- AA 1-30, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SUMO1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- B, M, Pig, Rat
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This SUMO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SUMO1.
- 克隆位点
- RB0629
- 亚型
- Ig Fraction
- Top Product
- Discover our top product SUMO1 Primary Antibody
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anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) antibody
SUMO1 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) antibodySUMO1 适用: 人, 大鼠 WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal SM1-495 unconjugated
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 1-101) antibodySUMO1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3D7 unconjugated
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (N-Term) antibodySUMO1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 52-79) antibodySUMO1 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 1-30) antibodySUMO1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 55-86) antibodySUMO1 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) antibodySUMO1 适用: 人 ELISA, IHC, FACS, IP 宿主: 兔 Monoclonal 5G3 unconjugated Recombinant Antibody
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (C-Term) antibodySUMO1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 55-86), (C-Term) antibodySUMO1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB0632 unconjugated
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- 应用备注
- IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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: "Human Regulatory Protein Ki-1/57 Is a Target of SUMOylation and Affects PML Nuclear Body Formation." in: Journal of proteome research, Vol. 16, Issue 9, pp. 3147-3157, (2018) (PubMed).
: "SUMOylation attenuates the aggregation propensity and cellular toxicity of the polyglutamine expanded ataxin-7." in: Human molecular genetics, Vol. 19, Issue 1, pp. 181-95, (2009) (PubMed).
: "Regulation of the Ets-1 transcription factor by sumoylation and ubiquitinylation." in: Oncogene, Vol. 26, Issue 3, pp. 395-406, (2007) (PubMed).
: "Carcinogen-induced histone alteration in normal human mammary epithelial cells." in: Carcinogenesis, Vol. 28, Issue 10, pp. 2184-92, (2007) (PubMed).
: "SUMO modification of the Ets-related transcription factor ERM inhibits its transcriptional activity." in: The Journal of biological chemistry, Vol. 280, Issue 26, pp. 24330-8, (2005) (PubMed).
: "SUMO promotes HDAC-mediated transcriptional repression." in: Molecular cell, Vol. 13, Issue 4, pp. 611-7, (2004) (PubMed).
: "Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcription." in: Nucleic acids research, Vol. 32, Issue 2, pp. 598-610, (2004) (PubMed).
: "Characterization of the localization and proteolytic activity of the SUMO-specific protease, SENP1." in: The Journal of biological chemistry, Vol. 279, Issue 1, pp. 692-703, (2003) (PubMed).
: "SUMO-1 marks the nuclear inclusions in familial neuronal intranuclear inclusion disease." in: Experimental neurology, Vol. 184, Issue 1, pp. 436-46, (2003) (PubMed).
: "Transforming growth factor-beta-mediated signaling via the p38 MAP kinase pathway activates Smad-dependent transcription through SUMO-1 modification of Smad4." in: The Journal of biological chemistry, Vol. 278, Issue 51, pp. 50833-42, (2003) (PubMed).
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: "Human Regulatory Protein Ki-1/57 Is a Target of SUMOylation and Affects PML Nuclear Body Formation." in: Journal of proteome research, Vol. 16, Issue 9, pp. 3147-3157, (2018) (PubMed).
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- 抗原
- SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))
- 别名
- SUMO1 (SUMO1 产品)
- 别名
- DAP1 antibody, GMP1 antibody, OFC10 antibody, PIC1 antibody, SENP2 antibody, SMT3 antibody, SMT3C antibody, SMT3H3 antibody, UBL1 antibody, hm:zeh0670 antibody, wu:fb74c02 antibody, wu:fd12c02 antibody, zgc:65934 antibody, zgc:85634 antibody, SUMO1 antibody, dap1 antibody, gmp1 antibody, ofc10 antibody, pic1 antibody, senp2 antibody, smt3 antibody, smt3c antibody, sumo-1 antibody, sumo1 antibody, ubl1 antibody, xsumo-1 antibody, xsumo1 antibody, ARABIDOPSIS THALIANA SMALL UBIQUITIN-LIKE MODIFIER 1 antibody, ATSUMO1 antibody, F10M23.180 antibody, F10M23_180 antibody, SMALL UBIQUITIN-LIKE MODIFIER 1 antibody, SUM1 antibody, SUMO 1 antibody, small ubiquitin-like modifier 1 antibody, pigSUMO1 antibody, SENTRIN antibody, SMTP3 antibody, SUMO-1 antibody, Smt3C antibody, Ubl1 antibody, small ubiquitin-like modifier 1 antibody, small ubiquitin-like modifier 1 S homeolog antibody, small ubiquitin-related protein 1 antibody, SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) antibody, SMT3 suppressor of mif two 3 homolog 1 (yeast) antibody, small ubiquitin-like modifier 1 L homeolog antibody, Sumo1 antibody, SUMO1 antibody, sumo1 antibody, sumo1.S antibody, sumo-1 antibody, sumo1.L antibody
- 背景
- Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. The SUMO family consists of SUMO1 and closely related homologs SUMO2, SUMO3, and SUMO4. Sumoylation has been shown to regulate a wide range of proteins, including MDM2, PIAS, PML, RanGAP1, RanBP2, p53, p73, HIPK2, TEL, c-Jun, Fas, Daxx, TNFRI, Topo-I, Topo-II, PARK2, WRN, Sp100, IkB-alpha, Androgen receptor (AR), GLUT1/4, CaMK, DNMT3B, TDG, HIF1A, CHD3, EXOSC9, RAD51, and viral targets such as CMV-IE1/2, EBV-BZLF1, and HPV/BPV-E1.
- 分子量
- 11557
- NCBI登录号
- NP_001005781, NP_001005782, NP_003343
- UniProt
- P63165
- 途径
- M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, Ubiquitin Proteasome Pathway
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