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MUC5AC 抗体 (CF®640R)

MUC5AC 适用: 人 IF, FACS, IHC (f) 宿主: 小鼠 Monoclonal MUC5AC-917 CF®640R
产品编号 ABIN6186272
发货至: 中国
  • 抗原 See all MUC5AC 抗体
    MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))
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    小鼠
    克隆类型
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    单克隆
    标记
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    This MUC5AC antibody is conjugated to CF®640R
    应用范围
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    Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    原理
    Mouse Monoclonal anti-Mucin 5AC (MUC5AC) (MUC5AC/917), CF640R Conjugate
    产品特性
    Mucin 5AC glycoprotein (MUC5AC) is a 641 kDa glycoprotein belonging to the superfamily of mucins. Mucins are high molecular weight glycoproteins produced by epithelial cells and can be divided into two families, secretory mucins and membrane bound mucins. MUC5AC is a mucus-forming secreted mucin that is found in normal gastric and tracheo-bronchial mucosa, but absent from normal colon. MUC5AC expression is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    免疫原
    Recombinant human MUC5AC protein
    克隆位点
    MUC5AC-917
    亚型
    IgG1 kappa
    Top Product
    Discover our top product MUC5AC Primary Antibody
  • 应用备注
    Immunohistology formalin-fixed 1-2 μg/mL
    • Does not react with rat, others not known
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Immunofluorescence 1-2 μg/mL
    • Optimal dilution for a specific application should be determined by user
    说明

    Stomach or gastric carcinoma.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100 μg/mL
    缓冲液
    PBS/0.1 % BSA/0.05 % azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from light
  • 抗原
    MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))
    别名
    Mucin 5AC (MUC5AC) (MUC5AC 产品)
    别名
    MUC5 antibody, TBM antibody, leB antibody, 2210005L13Rik antibody, MGM antibody, mucin 5AC, oligomeric mucus/gel-forming antibody, putative gastric mucin antibody, mucin 5, subtypes A and C, tracheobronchial/gastric antibody, mucin 2, oligomeric mucus/gel-forming antibody, MUC5AC antibody, Smp_144070 antibody, Muc5ac antibody, MUC2 antibody
    背景
    Apomucin Major Airway Glycoprotein, Mucin 5 subtype AC tracheobronchial, Mucin 5 Subtypes A And C, Mucin 5AC oligomeric mucus/gel forming, Tracheobronchial Mucin (TBM)
    分子量
    641 kDa
    基因ID
    4586, 534332
    UniProt
    P98088
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