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Nkx2-2 抗体 (AA 1-119) (CF®488A)

Nkx2-2 适用: 人 IF, FACS, IHC 宿主: 小鼠 Monoclonal NX2-1524 CF®488A
产品编号 ABIN6181465
发货至: 中国
  • 抗原 See all Nkx2-2 抗体
    Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
    抗原表位
    • 16
    • 9
    • 7
    • 7
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-119
    适用
    • 102
    • 50
    • 43
    • 22
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    宿主
    • 66
    • 46
    小鼠
    克隆类型
    • 59
    • 53
    单克隆
    标记
    • 50
    • 11
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Nkx2-2 antibody is conjugated to CF®488A
    应用范围
    • 47
    • 45
    • 39
    • 36
    • 30
    • 13
    • 9
    • 8
    • 7
    • 3
    • 1
    Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (IHC)
    原理
    Mouse Monoclonal anti-NKX2.2 (NX2/1524), CF488A Conjugate
    产品特性
    Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93 % and a specificity of 89 %, and aids in the differential diagnosis of small round cell tumors. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    免疫原
    Human recombinant NKX2.2 protein fragment (aa1-119) (exact sequence is proprietary)
    克隆位点
    NX2-1524
    亚型
    IgG1 kappa
    Top Product
    Discover our top product Nkx2-2 Primary Antibody
  • 应用备注
    Immunohistology (formalin) 1-2 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Immunofluorescence 1-2 μg/mL
    • Optimal dilution for a specific application should be determined by user
    说明

    Pancreas or Ewing s sarcoma

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100 μg/mL
    缓冲液
    PBS/0.1 % BSA/0.05 % azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from light
  • 抗原
    Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
    别名
    NKX2.2 (Nkx2-2 产品)
    别名
    XeNK-2 antibody, Xnkx2.2 antibody, nkx2-2-A antibody, nkx2.2 antibody, NKX-2.2 antibody, NKX2.2 antibody, NKX2B antibody, Nkx-2.2 antibody, Nkx2.2 antibody, tinman antibody, id:ibd5090 antibody, nk2.2 antibody, nkx2-2 antibody, wu:fc83b01 antibody, zgc:136536 antibody, NK2 homeobox 2 S homeolog antibody, NK2 homeobox 2 antibody, NK2 homeobox 2a antibody, nkx2-2.S antibody, NKX2-2 antibody, Nkx2-2 antibody, nkx2.2a antibody
    背景
    Homeobox protein NK-2 homolog B, NK2 transcription factor like protein B, NK2 transcription factor related locus 2, NKX22, Nkx2b, tinman
    分子量
    40-50 kDa
    基因ID
    4821, 516922
    UniProt
    O95096
    途径
    Dopaminergic Neurogenesis
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