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Nkx2-2 抗体 (N-Term)

Nkx2-2 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马, 绵羊 IHC, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2779575
发货至: 中国
  • 抗原 See all Nkx2-2 抗体
    Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
    抗原表位
    • 17
    • 9
    • 7
    • 7
    • 7
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 105
    • 49
    • 42
    • 22
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马, 绵羊
    宿主
    • 67
    • 48
    克隆类型
    • 63
    • 52
    多克隆
    标记
    • 53
    • 11
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Nkx2-2 antibody is un-conjugated
    应用范围
    • 49
    • 47
    • 38
    • 36
    • 30
    • 13
    • 13
    • 8
    • 7
    • 3
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB)
    序列
    MSLTNTKTGF SVKDILDLPD TNDEEGSVAE GPEEENEGPE PAKRAGPLGQ
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 100%, Sheep: 100%
    产品特性
    This is a rabbit polyclonal antibody against NKX2-2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human NKX2-2
    Top Product
    Discover our top product Nkx2-2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 273 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Owen, Kowalewski, Lessnick: "EWS/FLI mediates transcriptional repression via NKX2.2 during oncogenic transformation in Ewing's sarcoma." in: PLoS ONE, Vol. 3, Issue 4, pp. e1965, (2008) (PubMed).

  • 抗原
    Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
    别名
    NKX2-2 (Nkx2-2 产品)
    别名
    XeNK-2 antibody, Xnkx2.2 antibody, nkx2-2-A antibody, nkx2.2 antibody, NKX-2.2 antibody, NKX2.2 antibody, NKX2B antibody, Nkx-2.2 antibody, Nkx2.2 antibody, tinman antibody, id:ibd5090 antibody, nk2.2 antibody, nkx2-2 antibody, wu:fc83b01 antibody, zgc:136536 antibody, NK2 homeobox 2 S homeolog antibody, NK2 homeobox 2 antibody, NK2 homeobox 2a antibody, nkx2-2.S antibody, NKX2-2 antibody, Nkx2-2 antibody, nkx2.2a antibody
    背景
    Nkx2-2 contains 1 homeobox DNA-binding domain which is essential for interaction with OLIG2. Nkx2-2 may be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. The protein encoded by this gene contains a homeobox domain and may be involved in the morphogenesis of the central nervous system. This gene is found on chromosome 20 near NKX2-4, and these two genes appear to be duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear transcription factor.
    Alias Symbols: NKX2.2, NKX2B
    Protein Interaction Partner: Dlg4, SIN3A, HDAC1, OLIG2,
    Protein Size: 273
    分子量
    30 kDa
    基因ID
    4821
    NCBI登录号
    NM_002509, NP_002500
    UniProt
    O95096
    途径
    Dopaminergic Neurogenesis
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