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Recombinant Nkx2-2 抗体 (AA 1-119)

Nkx2-2 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rNX2-1523 unconjugated Recombinant Antibody
产品编号 ABIN6940204
发货至: 中国
  • 抗原 See all Nkx2-2 抗体
    Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
    抗体类型
    Recombinant Antibody
    抗原表位
    • 16
    • 9
    • 7
    • 7
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-119
    适用
    • 105
    • 50
    • 43
    • 22
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    宿主
    • 68
    • 47
    小鼠
    克隆类型
    • 62
    • 53
    单克隆
    标记
    • 53
    • 11
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Nkx2-2 antibody is un-conjugated
    应用范围
    • 49
    • 47
    • 38
    • 37
    • 30
    • 13
    • 13
    • 7
    • 7
    • 3
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    特异性
    Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93 % and a specificity of 89 %, and aids in the differential diagnosis of small round cell tumors.
    纯化方法
    Purified by Protein A/G
    免疫原
    Human recombinant NKX2.2 protein fragment (around aa1-119) (exact sequence is proprietary)
    克隆位点
    RNX2-1523
    亚型
    IgG1 kappa
    Top Product
    Discover our top product Nkx2-2 Primary Antibody
  • 应用备注

    Positive Control: Pancreas or Ewing's sarcoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
    别名
    NKX2-2 (Nkx2-2 产品)
    别名
    XeNK-2 antibody, Xnkx2.2 antibody, nkx2-2-A antibody, nkx2.2 antibody, NKX-2.2 antibody, NKX2.2 antibody, NKX2B antibody, Nkx-2.2 antibody, Nkx2.2 antibody, tinman antibody, id:ibd5090 antibody, nk2.2 antibody, nkx2-2 antibody, wu:fc83b01 antibody, zgc:136536 antibody, NK2 homeobox 2 S homeolog antibody, NK2 homeobox 2 antibody, NK2 homeobox 2a antibody, nkx2-2.S antibody, NKX2-2 antibody, Nkx2-2 antibody, nkx2.2a antibody
    分子量
    40-50kDa
    基因ID
    4821
    UniProt
    O95096
    途径
    Dopaminergic Neurogenesis
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