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NADPH Oxidase 4 抗体 (CF®568)

NOX4 适用: 人 WB, ELISA, FACS, IF, Coat 宿主: 小鼠 Monoclonal NOX4-1245 CF®568
产品编号 ABIN6165894
发货至: 中国
  • 抗原 See all NADPH Oxidase 4 (NOX4) 抗体
    NADPH Oxidase 4 (NOX4)
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This NADPH Oxidase 4 antibody is conjugated to CF®568
    应用范围
    • 79
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    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Coating (Coat)
    原理
    Mouse Monoclonal anti-NOX4 / NADPH-Oxidase-4 (NOX4/1245), CF568 Conjugate
    产品特性
    The superoxide-generating NADPH oxidase includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome, cytochrome b558, to form the active enzyme complex. The p22 and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. NOX4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. It is also expressed in fetal tissues, placenta, glioblastoma and vascular cells. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    免疫原
    Recombinant human NOX4 protein
    克隆位点
    NOX4-1245
    亚型
    IgG2b kappa
    Top Product
    Discover our top product NOX4 Primary Antibody
  • 应用备注
    Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Western blotting 0.5-1 μg/mL
    • ELISA For coating, order Ab without BSA
    • Optimal dilution for a specific application should be determined by user
    说明

    PC-12, JAR cells. Kidney

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100 μg/mL
    缓冲液
    PBS/0.1 % BSA/0.05 % azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from light
  • 抗原
    NADPH Oxidase 4 (NOX4)
    别名
    NOX4 / NADPH-Oxidase-4 (NOX4 产品)
    别名
    KOX antibody, KOX-1 antibody, RENOX antibody, AI648021 antibody, nox4 antibody, NOX4 antibody, NADPH oxidase 4 antibody, NOX4 antibody, Nox4 antibody, nox4 antibody, PTRG_09562 antibody
    背景
    Kidney oxidase-1, Kidney superoxide-producing NADPH oxidase, KOX-1, NADPH oxidase 4, Nox4, Renal NAD(P)H-oxidase, RENOX
    分子量
    70 kDa
    基因ID
    50507, 371036
    UniProt
    Q9NPH5
    途径
    Carbohydrate Homeostasis, Smooth Muscle Cell Migration
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