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HSP27 抗体 (CF®640R)

HSPB1 适用: 人, 大鼠, 小鼠, 绵羊, 小鸡, Chimpanzee WB, IF, FACS, IHC (f), ISt 宿主: 小鼠 Monoclonal HSPB1-774 CF®640R
产品编号 ABIN6164174
发货至: 中国
  • 抗原 See all HSP27 (HSPB1) 抗体
    HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))
    适用
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    人, 大鼠, 小鼠, 绵羊, 小鸡, Chimpanzee
    宿主
    • 226
    • 63
    小鼠
    克隆类型
    • 202
    • 86
    单克隆
    标记
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    This HSP27 antibody is conjugated to CF®640R
    应用范围
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    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunostaining (ISt)
    原理
    Mouse Monoclonal anti-HSP27 (HSPB1/774), CF640R Conjugate
    产品特性
    This antibody recognizes a 24-27 kDa estrogen-regulated protein, identified as heat shock protein 27 (hsp27). Hsp27 was recently found to be identical to the estrogen-induced ?p29? and ?24K? protein. About 50 % of breast carcinomas are positive for hsp27 especially those that are also positive for estrogen and/or progesterone receptor. HSP27 has also been implicated in drug resistance in cancer cells. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    免疫原
    Recombinant human HSPB1 protein
    克隆位点
    HSPB1-774
    亚型
    IgG1 kappa
    Top Product
    Discover our top product HSPB1 Primary Antibody
  • 应用备注
    Immunohistology formalin-fixed 0.5-1 μg/mL
    • Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
    • Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Western blotting 0.25-0.5 μg/mL
    • Optimal dilution for a specific application should be determined by user
    说明

    ~50% of Breast Carcinomas are positive for hsp27 especially those that are also positive for ER and/or PgR.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100 μg/mL
    缓冲液
    PBS/0.1 % BSA/0.05 % azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from light
  • 抗原
    HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))
    别名
    HSP27 (HSPB1 产品)
    别名
    CMT2F antibody, HMN2B antibody, HS.76067 antibody, HSP27 antibody, HSP28 antibody, Hsp25 antibody, SRP27 antibody, 27kDa antibody, Hsp27 antibody, cb153 antibody, cb660 antibody, hsp1 antibody, hsp25 antibody, hsp27 antibody, id:ibd2821 antibody, sb:cb660 antibody, zgc:103437 antibody, HSPB1 antibody, cmt2f antibody, hs.76067 antibody, hsp28 antibody, heat shock protein family B (small) member 1 antibody, heat shock protein 1 antibody, heat shock protein, alpha-crystallin-related, 1 antibody, heat shock protein family B (small) member 1 L homeolog antibody, HSPB1 antibody, Hspb1 antibody, hspb1 antibody, hspb1.L antibody
    分子量
    27 kDa
    基因ID
    3315, 520973
    UniProt
    P04792
    途径
    MAPK Pathway, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling
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