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Desmoglein 2 抗体 (CF®568)

DSG2 适用: 人 WB, IF, FACS 宿主: 小鼠 Monoclonal 6D8 CF®568
产品编号 ABIN6162208
发货至: 中国
  • 抗原 See all Desmoglein 2 (DSG2) 抗体
    Desmoglein 2 (DSG2)
    适用
    • 90
    • 37
    • 34
    • 7
    • 6
    • 5
    • 2
    • 2
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    • 2
    宿主
    • 72
    • 18
    小鼠
    克隆类型
    • 63
    • 27
    单克隆
    标记
    • 43
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    This Desmoglein 2 antibody is conjugated to CF®568
    应用范围
    • 77
    • 26
    • 22
    • 18
    • 16
    • 13
    • 13
    • 13
    • 10
    • 6
    • 6
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    原理
    Mouse Monoclonal anti-Desmoglein-2 (6D8), CF568 Conjugate
    产品特性
    This antibody recognizes the extracellular domain of human desmoglein-2 (DSG2), a member of the desmosomal cadherin family. Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Human Desmoglein-2 is a type I transmembrane glycoprotein of 1117 amino acid (aa) residues with a 23 aa signal peptide and a 25 aa propeptide. It differs from other classic cadherins by having four instead of five cadherin repeat domains in its extracellular region, and a much larger cytoplasmic region containing five desmoglein repeat domains which share homology with the cadherin repeats. Desmoglein-2 has been shown to be important in establishing cell-cell adhesion and function in epithelial cells. It was originally identified in colon carcinoma and colon, and was named HDGC (human desmoglein colon). Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    免疫原
    Recombinant human full-length DSG2 protein
    克隆位点
    6D8
    亚型
    IgG1 kappa
    Top Product
    Discover our top product DSG2 Primary Antibody
  • 应用备注
    Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Immunofluorescence 1-2 μg/mL
    • Western blotting 0.5-1 μg/mL
    • Optimal dilution for a specific application should be determined by user
    说明

    A431, HepG2 or K562 cells. Heart or Colon

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100 μg/mL
    缓冲液
    PBS/0.1 % BSA/0.05 % azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from light
  • 抗原
    Desmoglein 2 (DSG2)
    别名
    Desmoglein-2 (DSG2 产品)
    别名
    DSG2 antibody, dsc antibody, dsga antibody, si:dkeyp-51f12.6 antibody, wu:fj23f02 antibody, ARVC10 antibody, ARVD10 antibody, CDHF5 antibody, CMD1BB antibody, HDGC antibody, AA408168 antibody, D18Ertd293e antibody, desmoglein 2 antibody, desmoglein 2, tandem duplicate 1 antibody, DSG2 antibody, dsg2.1 antibody, dsg2 antibody, Dsg2 antibody
    背景
    ARVC10, ARVD10, Cadherin family member 5, CDHF5, CMD1BB, Desmoglein-2, DSG2, HDGC, Human Desmoglein Colon
    分子量
    ~165 kDa
    基因ID
    1829, 412597
    UniProt
    Q14126
    途径
    Cell-Cell Junction Organization
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