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Desmoglein 2 产品

(Desmoglein 2 (DSG2))
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jul 2008].

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Featured Desmoglein 2 Categories

Desmoglein 2 抗体

High quality antibodies with extensive validation data.

Desmoglein 2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Desmoglein 2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Desmoglein 2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (4)
Cat. No. ABIN7236806
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN6744433
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (3)
Cat. No. ABIN2855411
Quantity 100 μL
Datasheet Datasheet

Recommended Desmoglein 2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6955367
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1129572
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4882669
Quantity 96 tests
Datasheet Datasheet

Recommended Desmoglein 2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274500
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274502
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3079202
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Desmoglein 2 Products

Ebert, Tan, Johan, Min, Cockshell, Parham, Betterman, Szeto, Boyle, Silva, Peng, Zhang, Ruszkiewicz, Zannettino, Gronthos, Koblar, Harvey, Lopez, Shackleton, Bonder: "A non-canonical role for desmoglein-2 in endothelial cells: implications for neoangiogenesis." in: Angiogenesis, Vol. 19, Issue 4, pp. 463-86, (2016) (PubMed).

Pillai, Sankoorikal, Johnson, Seneviratne, Zurko, Brown, Hathout, Rose: "Directional secretomes reflect polarity-specific functions in an in vitro model of human bronchial epithelium." in: American journal of respiratory cell and molecular biology, Vol. 50, Issue 2, pp. 292-300, (2014) (PubMed).

Hummitzsch, Irving-Rodgers, Hatzirodos, Bonner, Sabatier, Reinhardt, Sado, Ninomiya, Wilhelm, Rodgers: "A new model of development of the mammalian ovary and follicles." in: PLoS ONE, Vol. 8, Issue 2, pp. e55578, (2013) (PubMed).

Kosanam, Prassas, Chrystoja, Soleas, Chan, Dimitromanolakis, Blasutig, Rückert, Gruetzmann, Pilarsky, Maekawa, Brand, Diamandis: "Laminin, gamma 2 (LAMC2): a promising new putative pancreatic cancer biomarker identified by proteomic analysis of pancreatic adenocarcinoma tissues." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 10, pp. 2820-32, (2013) (PubMed).

Wang, Beyer, Persson, Song, Li, Richter, Cao, van Rensburg, Yao, Hudkins, Yumul, Zhang, Yu, Fender, Hemminki, Lieber: "A new human DSG2-transgenic mouse model for studying the tropism and pathology of human adenoviruses." in: Journal of virology, Vol. 86, Issue 11, pp. 6286-302, (2012) (PubMed).

Schlegel, Meir, Heupel, Holthöfer, Leube, Waschke: "Desmoglein 2-mediated adhesion is required for intestinal epithelial barrier integrity." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 298, Issue 5, pp. G774-83, (2010) (PubMed).

Keim, Johnson, Wheelock, Wahl: "Generation and characterization of monoclonal antibodies against the proregion of human desmoglein-2." in: Hybridoma (2005), Vol. 27, Issue 4, pp. 249-58, (2008) (PubMed).

Asplund, Gry Björklund, Sundquist, Strömberg, Edlund, Ostman, Nilsson, Pontén, Lundeberg: "Expression profiling of microdissected cell populations selected from basal cells in normal epidermis and basal cell carcinoma." in: The British journal of dermatology, Vol. 158, Issue 3, pp. 527-38, (2008) (PubMed).

Hemmoranta, Hautaniemi, Niemi, Nicorici, Laine, Yli-Harja, Partanen, Jaatinen: "Transcriptional profiling reflects shared and unique characters for CD34+ and CD133+ cells." in: Stem cells and development, Vol. 15, Issue 6, pp. 839-51, (2007) (PubMed).

Ota, Amagai, Watanabe, Nishikawa: "No involvement of IgG autoantibodies against extracellular domains of desmoglein 2 in paraneoplastic pemphigus or inflammatory bowel diseases." in: Journal of dermatological science, Vol. 32, Issue 2, pp. 137-41, (2003) (PubMed).

Synonyms and alternative names related to Desmoglein 2

desmoglein 2 (DSG2), desmoglein 2, tandem duplicate 1 (dsg2.1), desmoglein 2 (dsg2), desmoglein 2 (Dsg2), AA408168, ARVC10, ARVD10, CDHF5, CMD1BB, D18Ertd293e, dsc, DSG2, dsga, HDGC, si:dkeyp-51f12.6, wu:fj23f02

Protein level used designations for Desmoglein 2

  • desmoglein 2
  • Dsg alpha
  • desmocollin a
  • desmoglein-2-like
  • HDGC
  • cadherin family member 5
  • desmoglein-2
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