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DEPTOR 产品

(DEP Domain Containing mTOR-Interacting Protein (DEPTOR))

Categories

Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes (By similarity).

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Featured DEPTOR Categories

DEPTOR 抗体

High quality antibodies with extensive validation data.

DEPTOR ELISA试剂盒

Reliable ELISA kits for a wide range of species.

DEPTOR 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DEPTOR 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro)
Validations
  • (2)
  • (4)
Cat. No. ABIN1387597
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
Cat. No. ABIN528709
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN7266738
Quantity 100 μL
Datasheet Datasheet

Recommended DEPTOR ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1129513
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1129514
Quantity 96 tests
Datasheet Datasheet

Recommended DEPTOR 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351458
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3078983
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3122407
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our DEPTOR Products

Suryawan, Davis: "Amino Acid- and Insulin-Induced Activation of mTORC1 in Neonatal Piglet Skeletal Muscle Involves Sestin2-GATOR2, Rag A/C-mTOR, and RHEB-mTOR Complex Formation." in: The Journal of nutrition, Vol. 148, Issue 6, pp. 825-833, (2019) (PubMed).

Yao, Tang, Zhang, Zhang, Liu, Liu, Gu, Zheng, Shang, Wang, Huang, Wei, Zhang, Zhang, Wu: "DEPTOR inhibits cell proliferation and confers sensitivity to dopamine agonist in pituitary adenoma." in: Cancer letters, Vol. 459, pp. 135-144, (2019) (PubMed).

Liu, Cai, Zhang, Liu, Luo, Xing, Du: "Deacetylation of NAT10 by Sirt1 promotes the transition from rRNA biogenesis to autophagy upon energy stress." in: Nucleic acids research, Vol. 46, Issue 18, pp. 9601-9616, (2019) (PubMed).

Baek, Ahn, Cho, Choi, Son, Yoon: "Simulated microgravity inhibits C2C12 myogenesis via phospholipase D2-induced Akt/FOXO1 regulation." in: Scientific reports, Vol. 9, Issue 1, pp. 14910, (2019) (PubMed).

Seok, Lee, Lee, Lee, Mun, Park, Chun, Lee, Lim, Kang: "Identification and Validation of SAA4 as a Rheumatoid Arthritis Prescreening Marker by Liquid Chromatography Tandem-mass Spectrometry." in: Molecules (Basel, Switzerland), Vol. 22, Issue 5, (2018) (PubMed).

Caron, Mouchiroud, Gautier, Labbé, Villot, Turcotte, Secco, Lamoureux, Shum, Gélinas, Marette, Richard, Sabatini, Laplante: "Loss of hepatic DEPTOR alters the metabolic transition to fasting." in: Molecular metabolism, Vol. 6, Issue 5, pp. 447-458, (2017) (PubMed).

Caron, Labbé, Lanfray, Blanchard, Villot, Roy, Sabatini, Richard, Laplante: "Mediobasal hypothalamic overexpression of DEPTOR protects against high-fat diet-induced obesity." in: Molecular metabolism, Vol. 5, Issue 2, pp. 102-12, (2016) (PubMed).

Song, Yoon: "PLD1 regulates adipogenic differentiation through mTOR - IRS-1 phosphorylation at serine 636/639." in: Scientific reports, Vol. 6, pp. 36968, (2016) (PubMed).

Carbonneau, M Gagné, Lalonde, Germain, Motorina, Guiot, Secco, Vincent, Tumber, Hulea, Bergeman, Oppermann, Jones, Laplante, Topisirovic, Petrecca, Huot, Mallette: "The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway." in: Nature communications, Vol. 7, pp. 12700, (2016) (PubMed).

Liu, Zhang, Liu, Li, Zhang, Li, Liu, Huang, Shen, Gu, Gao, Wu, Wu: "High DEPTOR expression correlates with poor prognosis in patients with esophageal squamous cell carcinoma." in: OncoTargets and therapy, Vol. 8, pp. 3449-55, (2015) (PubMed).

Synonyms and alternative names related to DEPTOR

DEP domain containing MTOR interacting protein (DEPTOR), DEP domain containing MTOR-interacting protein (Deptor), DEP domain containing MTOR-interacting protein (DEPTOR), 4731402B04Rik, 9130412E02Rik, D15Ertd336e, D15Ertd597e, DEP.6, DEPDC6, Depdc6, Depdc6-001, Depdc6-002, mKIAA4200, R75183, RAPGEF4, RGD1561030

Protein level used designations for DEPTOR

  • DEP domain containing MTOR-interacting protein
  • DEP domain containing 6
  • DEP domain containing mTOR interacting protein
  • DEP domain-containing mTOR-interacting protein
  • DEP domain-containing protein 6
  • Rap guanine nucleotide exchange factor (GEF) 4
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